CD95L (also known as FasL or CD178) is a member of the tumor necrosis family (TNF)
superfamily. Although this transmembrane ligand has been mainly considered as a potent …

Although the interaction of CD95L (also known as FasL) with its so-called death receptor
CD95 (Fas) induces an apoptotic signal responsible for the elimination of infected and …

The role of CD95/Fas ligand (CD95L/FasL) in the induction of CD95-mediated extrinsic
apoptosis is well characterized. Trimerized, membrane-bound CD95L ligates the CD95 …

Abstract The Fas/FasL system plays a central role in the physiological regulation of
apoptosis and has been implicated in the pathogenesis of several neoplasms and diseases …

Binding of CD95, a cell surface death receptor, to its homologous ligand CD95L, transduces
a cascade of downstream signals leading to apoptosis crucial for immune homeostasis and …

Background: Obesity and diabetes are major public health problems. Resistin is an
adipokine that links the two diseases. There are few reports regarding colostrum cells and …

Study of the initial steps of the CD95-mediated signaling pathways is a field of intense
research and a long list of actors has been described in the literature. Nonetheless, the …

可变剪接(alternative splicing, AS) 是一种调节基因表达的一般机制, 高达95%
的人类基因经历了AS, 这意味着这种转录后调节机制对几乎所有细胞过程都至关重要. AS …

Soluble Fas ligand (sFasL, sCD95L) and its specific soluble binders, soluble Fas receptor
(sFas, sCD95) and decoy receptor 3 (DcR3), have been investigated as possible clinical …

Abstract CD95/Fas ligand (CD95L) is a well characterized activator of extrinsic apoptosis.
CD95L protein binds to its cognate receptor, CD95/Fas/APO-1, inducing apoptotic signaling …