[HTML][HTML] APOE in the normal brain

SA Flowers, GW Rebeck - Neurobiology of disease, 2020 - Elsevier
The APOE4 protein affects the primary neuropathological markers of Alzheimer's disease
(AD): amyloid plaques, neurofibrillary tangles, and gliosis. These interactions have been …

Blast-related traumatic brain injury: current concepts and research considerations

DW Bryden, JI Tilghman… - Journal of experimental …, 2019 - journals.sagepub.com
Traumatic brain injury (TBI) is a well-known consequence of participation in activities such
as military combat or collision sports. But the wide variability in eliciting circumstances and …

[HTML][HTML] Interaction of APOE4 alleles and PET tau imaging in former contact sport athletes

A Vasilevskaya, F Taghdiri, C Burke, A Tarazi… - NeuroImage: Clinical, 2020 - Elsevier
Background Genetic polymorphisms like apolipoprotein E (APOE) and microtubule-
associated protein tau (MAPT) genes increase the risk of neurodegeneration. Methods 38 …

[HTML][HTML] Toward a global and reproducible science for brain imaging in neurotrauma: the ENIGMA adult moderate/severe traumatic brain injury working group

A Olsen, T Babikian, ED Bigler… - Brain imaging and …, 2021 - Springer
The global burden of mortality and morbidity caused by traumatic brain injury (TBI) is
significant, and the heterogeneity of TBI patients and the relatively small sample sizes of …

Network analysis of research on mild traumatic brain injury in US military service members and veterans during the past decade (2010-2019)

SR Eagle, MW Collins, MN Dretsch… - The Journal of Head …, 2021 - journals.lww.com
Objective: To evaluate trends in the extant literature on mild traumatic brain injury (mTBI) in
military service members and veterans using network analysis based on a comprehensive …

Characterization of Million Veteran Program (MVP) enrollees with Comprehensive Traumatic Brain Injury Evaluation (CTBIE) data: an analysis of neurobehavioral …

ED Ozturk, C Chanfreau-Coffinier… - Journal of psychiatric …, 2022 - Elsevier
The purpose of this study was to examine neurobehavioral symptom reporting in a large
sample of military veterans (N= 12,144) who completed the Comprehensive Traumatic Brain …

Apolipoprotein E e4 is associated with worse self-reported neurobehavioral symptoms following uncomplicated mild traumatic brain injury in US military service …

RT Lange, VC Merritt, TA Brickell, CL Dalgard… - Behavioural brain …, 2021 - Elsevier
Past research has found a relationship between the apolipoprotein E (APOE) e4 allele and
worse neurobehavioral functioning following mild traumatic brain injury (MTBI) in civilian …

Genetic Variants and Persistent Impairment Following Mild Traumatic Brain Injury: A Systematic Review

CM Feigen, MF Charney, S Glajchen… - The Journal of Head …, 2024 - journals.lww.com
Objective: The purpose of this review is to systematically assess primary research
publications on known genetic variants, which modify the risk for symptoms or dysfunction …

Interaction between APOE ɛ4 and age is associated with emotional distress one year after moderate-severe traumatic brain injury

C Anderson, J Carmichael, AJ Hicks, R Burke… - Journal of …, 2023 - liebertpub.com
Emotional distress is common following moderate-severe traumatic brain injury (TBI) and is
associated with poorer post-injury outcomes. Previously investigated sociodemographic …

Apolipoprotein E (APOE) ε4 status moderates the relationship between close-range blast exposure and cognitive functioning

T Wooten, DR Sullivan, MW Logue… - Journal of the …, 2021 - cambridge.org
Objectives: Recent studies suggest that close-range blast exposure (CBE), regardless of
acute concussive symptoms, may have negative long-term effects on brain health and …