Iridoids are a class of active compounds that widely exist in the plant kingdom. In recent
years, with advances in phytochemical research, many compounds with novel structure and …

Biological and Pharmacological Activities of Iridoids: Recent Developments Page 1 Mini-Reviews
in Medicinal Chemistry, 2008, 8, 399-420 399 1389-5575/08 $55.00+.00 © 2008 Bentham …

A variety of drug transporters expressed in the body control the fate of drugs by affecting
absorption, distribution, and elimination processes. In the small intestine, transporters …

The multi-drug resistance protein 2 (MRP2; ABCC2) is an ATP-binding cassette transporter
playing an important role in detoxification and chemoprotection by transporting a wide range …

Genipin is an aglycone derived from the geniposide, the most abundant iridoid glucoside
constituent of Gardenia jasminoides Ellis. For decades, genipin is the focus of studies as a …

ABCC2/Abcc2 (MRP2/Mrp2) is expressed at major physiological barriers, such as the
canalicular membrane of liver cells, kidney proximal tubule epithelial cells, enterocytes of …

It is well known that transporter proteins play a key role in governing drug absorption,
distribution, and elimination in the body, and, accordingly, they are now considered as …

Background and Purpose Activation of glucagon‐like peptide‐1 (GLP‐1) receptor exerts a
range of cardioprotective effects. Geniposide is an agonist of GLP‐1 receptor, but its role in …

The protective action of ursodeoxycholic acid (UDCA) in cholestatic liver diseases may be
mediated by choleresis, detoxification, and cytoprotection against oxidative stress. Nrf2, one …

Chitosan and alginate hydrogels are attractive because they are highly biocompatible and
suitable for developing nanomedicine microcapsules. Here we fabricated a …