Secular changes and worldwide variations in incidence rates of colorectal cancer, along
with results from twin and migrant studies, provide compelling evidence that environmental …

IGF-I is a multipotent growth factor with important actions on normal tissue growth and
regeneration. In addition, IGF-I has been suggested to have beneficial effects on glucose …

Both insulin and IGF-1 have been implicated in control of retinal endothelial cell growth,
neovascularization, and diabetic retinopathy. To precisely define the role of insulin and IGF …

Much attention has focused on the effects of leptin as a central satiety agent. There is now a
significant amount of evidence that leptin is active in the periphery. This review focuses on …

A Western lifestyle has been implicated in the pathogenesis of prostate cancer. However, no
clear association between obesity and prostate cancer has been shown. Leptin may …

Diabetes complications can be related to the long duration of the disease or chronic
hyperglycemia. The follow-up of diabetic patients is based on the control of chronic …

We have previously demonstrated that IGF-binding protein-1 (IGFBP-1) levels rise steadily
during fasting, following an inverse relationship with insulin. The function of the IGFBP-1 rise …

Type 1 diabetes mellitus (T1DM) is a chronic autoimmune disease targeting the pancreatic
beta-cells and rendering the person hypoinsulinemic and hyperglycemic. Despite …

Background A variety of demographic and clinical variables are acknowledged as risk
factors for delirium; a syndrome thought to be mediated by abnormalities in a wide range of …

Objective: The aim of the present study was to investigate the relationship between diabetes
mellitus (DM) and tumor features in patients with non‐muscle invasive bladder cancer …