[HTML][HTML] The consequences of our changing environment on life threatening and debilitating fungal diseases in humans

N Van Rhijn, M Bromley - Journal of Fungi, 2021 - mdpi.com
Human activities have significantly impacted the environment and are changing our climate
in ways that will have major consequences for ourselves, and endanger animal, plant and …

[HTML][HTML] The emerging role of extracellular vesicles in fungi: A double-edged sword

Y Lai, B Jiang, F Hou, X Huang, B Ling, H Lu… - Frontiers in …, 2023 - frontiersin.org
Fungi are eukaryotic microorganisms found in nature, which can invade the human body
and cause tissue damage, inflammatory reactions, organ dysfunctions, and diseases. These …

[HTML][HTML] What's New in Cryptococcus gattii: From Bench to Bedside and Beyond

J Beardsley, A Dao, C Keighley, K Garnham… - Journal of Fungi, 2022 - mdpi.com
Cryptococcus species are a major cause of life-threatening infections in
immunocompromised and immunocompetent hosts. While most disease is caused by …

[HTML][HTML] Microglia are not protective against cryptococcal meningitis

SH Mohamed, MS Fu, S Hain, A Alselami… - Nature …, 2023 - nature.com
Microglia provide protection against a range of brain infections including bacteria, viruses
and parasites, but how these glial cells respond to fungal brain infections is poorly …

Fungal immunity and pathogenesis in mammals versus the invertebrate model organism Galleria mellonella

D FQ Smith, A Casadevall - Pathogens and disease, 2021 - academic.oup.com
In recent decades, Galleria mellonella (Lepidoptera: Pyralidae) have emerged as a model
system to explore experimental aspects of fungal pathogenesis. The benefits of the G …

“We've got to get out”—Strategies of human pathogenic fungi to escape from phagocytes

J Sonnberger, L Kasper, T Lange… - Molecular …, 2024 - Wiley Online Library
Human fungal pathogens are a deadly and underappreciated risk to global health that most
severely affect immunocompromised individuals. A virulence attribute shared by some of the …

[HTML][HTML] The Cryptococcus gattii species complex: Unique pathogenic yeasts with understudied virulence mechanisms

L Saidykhan, CU Onyishi, RC May - PLoS Neglected Tropical …, 2022 - journals.plos.org
Members of Cryptococcus gattii/neoformans species complex are the etiological agents of
the potentially fatal human fungal infection cryptococcosis. C. gattii and its sister species …

[HTML][HTML] Melanized root-associated fungi: key players in plant–soil systems

T Netherway, M Bahram - Trends in Microbiology, 2024 - cell.com
Melanized root-associated fungi are a group of fungi that produce melanized structures and
form root associations, including different mycorrhizal and endophytic symbioses with plants …

Laccase affects the rate of Cryptococcus neoformans nonlytic exocytosis from macrophages

SO Frazão, HR Sousa, LG Silva, JS Folha… - MBio, 2020 - Am Soc Microbiol
Nonlytic exocytosis is a process in which previously ingested microbes are expelled from
host phagocytes with the concomitant survival of both cell types. This process has been …

[HTML][HTML] Cryptococcal virulence in humans: Learning from translational studies with clinical isolates

HR De Sousa, S Frazão, GP Oliveira Júnior… - Frontiers in Cellular …, 2021 - frontiersin.org
Cryptococcosis, an invasive mycosis caused by Cryptococcus spp, kills between 20% and
70% of the patients who develop it. There are no vaccines for prevention, and treatment is …