Reactive gliosis in Alzheimer's disease: a crucial role for cognitive impairment and memory loss
RAL De Sousa - Metabolic Brain Disease, 2022 - Springer
Alzheimer's disease (AD) is a neurodegenerative disorder that leads to cognitive decline
and memory loss. Insulin resistance in central nervous system (CNS) is a common feature in …
and memory loss. Insulin resistance in central nervous system (CNS) is a common feature in …
Pathobiological subtypes of Alzheimer disease
KA Jellinger - Dementia and Geriatric Cognitive Disorders, 2021 - karger.com
Alzheimer disease (AD), the most common form of dementia, is a heterogenous disorder
with various pathobiological subtypes. In addition to the 4 major subtypes based on the …
with various pathobiological subtypes. In addition to the 4 major subtypes based on the …
Assessing reactive astrogliosis with 18F-SMBT-1 across the Alzheimer disease spectrum
VL Villemagne, R Harada, V Doré… - Journal of Nuclear …, 2022 - Soc Nuclear Med
A neuroinflammatory reaction in Alzheimer disease (AD) brains involves reactive astrocytes
that overexpress monoamine oxidase-B (MAO-B). 18F-(S)-(2-methylpyrid-5-yl)-6-[(3-fluoro-2 …
that overexpress monoamine oxidase-B (MAO-B). 18F-(S)-(2-methylpyrid-5-yl)-6-[(3-fluoro-2 …
Astrocyte adaptation in Alzheimer's disease: a focus on astrocytic P2X7R
P Beltran-Lobo, MJ Reid… - Essays in …, 2023 - portlandpress.com
Astrocytes are key homeostatic and defensive cells of the central nervous system (CNS).
They undertake numerous functions during development and in adulthood to support and …
They undertake numerous functions during development and in adulthood to support and …
Astroglial tracer BU99008 detects multiple binding sites in Alzheimer's disease brain
A Kumar, NA Koistinen, ML Malarte, I Nennesmo… - Molecular …, 2021 - nature.com
With reactive astrogliosis being established as one of the hallmarks of Alzheimer's disease
(AD), there is high interest in developing novel positron emission tomography (PET) tracers …
(AD), there is high interest in developing novel positron emission tomography (PET) tracers …
Astroglia in Alzheimer's disease
A Verkhratsky, V Parpura… - Neuroglia in …, 2019 - Springer
Alzheimer's disease is the most common cause of dementia. Cellular changes in the brains
of the patients suffering from Alzheimer's disease occur well in advance of the clinical …
of the patients suffering from Alzheimer's disease occur well in advance of the clinical …
Development of Alzheimer's disease biomarkers: From CSF-to blood-based biomarkers
S Mankhong, S Kim, S Lee, HB Kwak, DH Park, KL Joa… - Biomedicines, 2022 - mdpi.com
In the 115 years since the discovery of Alzheimer's disease (AD), our knowledge, diagnosis,
and therapeutics have significantly improved. Biomarkers are the primary tools for clinical …
and therapeutics have significantly improved. Biomarkers are the primary tools for clinical …
Imaging and neuropathological findings in patients with post COVID-19 neurological syndrome—a review
J Okrzeja, A Garkowski, B Kubas… - Frontiers in …, 2023 - frontiersin.org
Post COVID-19 syndrome is determined as signs and symptoms that appear during or after
an infection consistent with SARS-CoV-2 disease, persist for more than 12 weeks and are …
an infection consistent with SARS-CoV-2 disease, persist for more than 12 weeks and are …
Plasma glial fibrillary acidic protein levels differ along the spectra of amyloid burden and clinical disease stage
Background: Measuring plasma glial fibrillary acidic protein (GFAP) alongside cortical
amyloid-β (Aβ) may shed light on astrocytic changes in aging and Alzheimer's disease (AD) …
amyloid-β (Aβ) may shed light on astrocytic changes in aging and Alzheimer's disease (AD) …
Emerging role of miR-21-5p in neuron–glia dysregulation and exosome transfer using multiple models of Alzheimer's disease
Alzheimer's disease (AD) is a neurodegenerative disorder associated with neuron–glia
dysfunction and dysregulated miRNAs. We previously reported upregulated miR-124/miR …
dysfunction and dysregulated miRNAs. We previously reported upregulated miR-124/miR …