Historically considered as accessory cells to neurons, there is an increasing interest in the
role of astrocytes in normal and pathological conditions. Astrocytes are involved in …

In a healthy physiological context, astrocytes are multitasking cells contributing to central
nervous system (CNS) homeostasis, defense, and immunity. In cell culture or rodent models …

GV1001 protects neural cells from amyloid-β (Aβ) toxicity and other stressors in in vitro
studies and demonstrates clinically beneficial effects in patients with moderate to severe …

Alzheimer's disease (AD) is a common neurodegenerative disease that is accompanied by
pronounced neuroinflammatory responses mainly characterized by marked microgliosis and …

The neuroinflammation induced by amyloid-β (Aβ) has emerged as an important role in
onset and progression of Alzheimer's disease (AD). Hence, regulating the inflammatory …

Alzheimer's disease (AD) is a common neurodegenerative disease, always clinically
manifesting with memory loss and other cognitive abilities serious enough to interfere with …

Neurons, glial cells and blood vessels are collectively referred to as the neurovascular unit
(NVU). In the Alzheimer's disease (AD) brain, the main components of the NVU undergo …

Alzheimer's disease (AD) is the leading cause of late-onset dementia, and there exists an
unmet medical need for effective treatments for AD. The accumulation of neurotoxic amyloid …

Alzheimer's disease (AD) is a common age-related neurodegenerative disease that leads to
memory loss and cognitive function damage due to intracerebral neurofibrillary tangles …

Astrocytes respond to any pathological condition in the central nervous system (CNS)
including Alzheimer's disease (AD), and this response is called astrocyte reactivity. Astrocyte …