miRNA: a promising therapeutic target in cancer
microRNAs are small non-coding RNAs that regulate several genes post-transcriptionally by
complementarity pairing. Since discovery, they have been reported to be involved in a …
complementarity pairing. Since discovery, they have been reported to be involved in a …
Exosomes as bio-inspired nanocarriers for RNA delivery: preparation and applications
A Amiri, R Bagherifar, E Ansari Dezfouli… - Journal of Translational …, 2022 - Springer
Nanocarriers as drug/biomolecule delivery systems have been significantly developed
during recent decades. Given the stability, reasonable delivery efficiency, and safety of …
during recent decades. Given the stability, reasonable delivery efficiency, and safety of …
[HTML][HTML] Exosome regulation of immune response mechanism: Pros and cons in immunotherapy
Due to its multiple features, including the ability to orchestrate remote communication
between different tissues, the exosomes are the extracellular vesicles arousing the highest …
between different tissues, the exosomes are the extracellular vesicles arousing the highest …
Therapeutic Copolymer from Salicylic Acid and l-Phenylalanine as a Nanosized Drug Carrier for Orthotopic Breast Cancer with Lung Metastasis
Y Meng, S Han, J Yin, J Wu - ACS Applied Materials & Interfaces, 2023 - ACS Publications
Nanoparticle (NP)-mediated drug delivery systems are promising for treating various
diseases. However, clinical translation has been delayed by a variety of limitations, such as …
diseases. However, clinical translation has been delayed by a variety of limitations, such as …
[HTML][HTML] Lipid carriers for mRNA delivery
W Zhang, Y Jiang, Y He, H Boucetta, J Wu… - … Pharmaceutica Sinica B, 2023 - Elsevier
Messenger RNA (mRNA) is the template for protein biosynthesis and is emerging as an
essential active molecule to combat various diseases, including viral infection and cancer …
essential active molecule to combat various diseases, including viral infection and cancer …
Hyaluronic acid-coated bovine milk exosomes for achieving tumor-specific intracellular delivery of miRNA-204
Cell type-specific drug delivery is a straightforward strategy to achieve targeted cancer
therapy and reduce side effects. Hyaluronic acid (HA), an US Food and Drug Administration …
therapy and reduce side effects. Hyaluronic acid (HA), an US Food and Drug Administration …
Exosome-based drug delivery systems in cancer therapy
T Wang, Y Fu, S Sun, C Huang, Y Yi, J Wang… - Chinese Chemical …, 2023 - Elsevier
Exosome, which is a kind of extracellular vesicles with size around 40-160 nm, plays an
important role in cell-to-cell communication in multiple diseases. Especially in tumor …
important role in cell-to-cell communication in multiple diseases. Especially in tumor …
High-throughput quantitative detection of triple-negative breast cancer-associated expressed miRNAs by rolling circle amplification on fluorescence-encoded …
J Liu, L Zhang, W Zeng, L Zhang, N He, Z Lu - Chinese Chemical Letters, 2023 - Elsevier
Compared with other types of breast cancer, triple-negative breast cancer (TNBC) has the
characteristics of a high degree of malignancy and poor prognosis. Early diagnosis of TNBC …
characteristics of a high degree of malignancy and poor prognosis. Early diagnosis of TNBC …
Surface engineering of HEK293 cell-derived extracellular vesicles for improved pharmacokinetic profile and targeted delivery of IL-12 for the treatment of …
J Zhang, H Song, Y Dong, G Li, J Li, Q Cai… - International journal …, 2023 - Taylor & Francis
Background Extracellular vesicles (EVs) are considered a promising drug delivery platform.
Naïve EVs face numerous issues that limit their applications, such as fast clearance, hepatic …
Naïve EVs face numerous issues that limit their applications, such as fast clearance, hepatic …
A state-of-the-art analysis of pharmacological delivery and artificial intelligence techniques for inner ear disease treatment
W Li, N Zheng, Q Zhou, MS Alqahtani… - Environmental …, 2023 - Elsevier
Over the last several decades, both the academic and therapeutic fields have seen
significant progress in the delivery of drugs to the inner ear due to recent delivery methods …
significant progress in the delivery of drugs to the inner ear due to recent delivery methods …