The etiology of hepatocellular carcinoma and consequences for treatment

AJ Sanyal, SK Yoon, R Lencioni - The oncologist, 2010 - academic.oup.com
Most patients with hepatocellular carcinoma (HCC) have liver cirrhosis, which develops
following long periods of chronic liver disease. Cirrhosis is characterized by a decrease in …

Treatment of intermediate/advanced hepatocellular carcinoma in the clinic: how can outcomes be improved?

R Lencioni, XP Chen, L Dagher, AP Venook - The oncologist, 2010 - academic.oup.com
Hepatocellular carcinoma (HCC) is a complex condition associated with a poor prognosis.
Treatment outcomes are affected by multiple variables, including liver function, performance …

Naringenin (citrus flavonone) induces growth inhibition, cell cycle arrest and apoptosis in human hepatocellular carcinoma cells

D Arul, P Subramanian - Pathology & Oncology Research, 2013 - Springer
Search for new substances with antiproliferative activity and apoptosis inducing potential
towards HepG2 cells is important since HCC is notoriously resistant to conventional …

Activatable nanocomposite probe for preoperative location and intraoperative navigation for orthotopic hepatic tumor resection via MSOT and aggregation-induced …

Z Zeng, J Ouyang, L Sun, C Zeng, F Zeng… - Analytical …, 2020 - ACS Publications
The precise location of tumor and completeness of surgical resection are critical to
successful tumor surgery; thus, the method capable of preoperatively locating a tumor site …

Evaluation of midkine as a diagnostic serum biomarker in hepatocellular carcinoma

WW Zhu, JJ Guo, L Guo, HL Jia, M Zhu, JB Zhang… - Clinical Cancer …, 2013 - AACR
Purpose: To evaluate the value of serum midkine (MDK) as a diagnostic biomarker in
hepatocellular carcinoma, particularly for those with negative alpha-fetoprotein (AFP) and at …

Comparative effectiveness of first‐line radiofrequency ablation versus surgical resection and transplantation for patients with early hepatocellular carcinoma

OC Kutlu, JA Chan, TA Aloia, YS Chun, AO Kaseb… - Cancer, 2017 - Wiley Online Library
BACKGROUND Significant controversy exists as to which treatment modality is most
effective for small, solitary hepatocellular carcinomas (HCCs): radiofrequency ablation …

Sphingosine kinase 1 promotes tumour cell migration and invasion via the S1P/EDG 1 axis in hepatocellular carcinoma

M Bao, Z Chen, Y Xu, Y Zhao, R Zha… - Liver …, 2012 - Wiley Online Library
Abstract Background/Aims Sphingosine kinase 1 (SphK1), which phosphorylates
sphingosine to sphingosine‐1‐phosphate (S1P), is overexpressed in various types of …

Hepatocellular carcinoma screening and surveillance: practice guidelines and real-life practice

C Zhao, MH Nguyen - Journal of clinical gastroenterology, 2016 - journals.lww.com
Hepatocellular carcinoma (HCC) is the seventh most common malignancy worldwide. HCC
meets all the criteria established by the World Health Organization for performing …

[HTML][HTML] Adjuvant heparanase inhibitor PI-88 therapy for hepatocellular carcinoma recurrence

CJ Liu, J Chang, PH Lee, DY Lin, CC Wu… - World Journal of …, 2014 - ncbi.nlm.nih.gov
AIM: To demonstrate that administering heparanase inhibitor PI-88 at 160 mg/d is safe and
promising in reducing hepatocellular carcinoma (HCC) recurrence for up to 3 year following …

[HTML][HTML] Adjuvant transarterial chemoembolization after curative resection of hepatocellular carcinoma: propensity score analysis

JH Jiang, Z Guo, HF Lu, XB Wang… - World journal of …, 2015 - ncbi.nlm.nih.gov
AIM: To compare survival and recurrence in hepatocellular carcinoma (HCC) patients who
did or did not receive adjuvant transarterial chemoembolization (TACE). METHODS: A …