Nanoparticle-based drug delivery in cancer therapy and its role in overcoming drug resistance

Y Yao, Y Zhou, L Liu, Y Xu, Q Chen, Y Wang… - Frontiers in molecular …, 2020 - frontiersin.org
Nanotechnology has been extensively studied and exploited for cancer treatment as
nanoparticles can play a significant role as a drug delivery system. Compared to …

Non-ionic surfactants for stabilization of polymeric nanoparticles for biomedical uses

H Cortés, H Hernández-Parra, SA Bernal-Chávez… - Materials, 2021 - mdpi.com
Surfactants are essential in the manufacture of polymeric nanoparticles by emulsion
formation methods and to preserve the stability of carriers in liquid media. The deposition of …

Emerging nanotechnology-based therapeutics to combat multidrug-resistant cancer

P Yadav, SV Ambudkar, N Rajendra Prasad - Journal of …, 2022 - Springer
Cancer often develops multidrug resistance (MDR) when cancer cells become resistant to
numerous structurally and functionally different chemotherapeutic agents. MDR is …

A review of stimuli-responsive nanocarriers for drug and gene delivery

S Ganta, H Devalapally, A Shahiwala… - Journal of controlled …, 2008 - Elsevier
Nanotechnology has shown tremendous promise in target-specific delivery of drugs and
genes in the body. Although passive and active targeted-drug delivery has addressed a …

[HTML][HTML] Theranostic polymeric nanoparticles as a new approach in cancer therapy and diagnosis: a review

SM Hosseini, J Mohammadnejad, S Salamat… - Materials Today …, 2023 - Elsevier
The theranostic term is a revolutionary topic in cancer treatment, combining therapeutic and
diagnostic. Theranostic provides an opportunity for diagnosis and response assessment …

[HTML][HTML] Paclitaxel nano-delivery systems: a comprehensive review

P Ma, RJ Mumper - Journal of nanomedicine & nanotechnology, 2013 - ncbi.nlm.nih.gov
Paclitaxel is one of the most effective chemotherapeutic drugs ever developed and is active
against a broad range of cancers, such as lung, ovarian, and breast cancers. Due to its low …

Nanodrug delivery in reversing multidrug resistance in cancer cells

S Kapse-Mistry, T Govender, R Srivastava… - Frontiers in …, 2014 - frontiersin.org
Different mechanisms in cancer cells become resistant to one or more chemotherapeutics is
known as multidrug resistance (MDR) which hinders chemotherapy efficacy. Potential …

Role of integrated cancer nanomedicine in overcoming drug resistance

AK Iyer, A Singh, S Ganta, MM Amiji - Advanced drug delivery reviews, 2013 - Elsevier
Cancer remains a major killer of mankind. Failure of conventional chemotherapy has
resulted in recurrence and development of virulent multi drug resistant (MDR) phenotypes …

Nanopreparations to overcome multidrug resistance in cancer

NR Patel, BS Pattni, AH Abouzeid… - Advanced drug delivery …, 2013 - Elsevier
Multidrug resistance is the most widely exploited phenomenon by which cancer eludes
chemotherapy. Broad variety of factors, ranging from the cellular ones, such as over …

Recent advances in ovarian cancer: therapeutic strategies, potential biomarkers, and technological improvements

S Akter, MA Rahman, MN Hasan, H Akhter, P Noor… - Cells, 2022 - mdpi.com
Aggressive and recurrent gynecological cancers are associated with worse prognosis and a
lack of effective therapeutic response. Ovarian cancer (OC) patients are often diagnosed in …