How can behavioural science help us design better trials?
Background Clinical trials remain the cornerstone of evidence-based health care. As of July
1, 2021, there were 382,313 clinical trials registered on ClinicalTrials. gov, an average of …
1, 2021, there were 382,313 clinical trials registered on ClinicalTrials. gov, an average of …
Starting a conversation about estimands with public partners involved in clinical trials: a co-developed tool
Background Clinical trials aim to draw conclusions about the effects of treatments, but a trial
can address many different potential questions. For example, does the treatment work well …
can address many different potential questions. For example, does the treatment work well …
How do we know a treatment is good enough? A survey of non-inferiority trials
Background Non-inferiority and equivalence trials aim to determine whether a new treatment
is good enough (non-inferior) or as good as (equivalent to) another treatment. To inform the …
is good enough (non-inferior) or as good as (equivalent to) another treatment. To inform the …
Patient and public involvement in numerical aspects of trials (PoINT): exploring patient and public partners experiences and identifying stakeholder priorities
Background and aims Patient and public involvement is increasingly common in trials, but its
quality remains variable in a lot of settings. Many key decisions in trials involve numbers, but …
quality remains variable in a lot of settings. Many key decisions in trials involve numbers, but …
Reporting of and explanations for under-recruitment and over-recruitment in pragmatic trials: a secondary analysis of a database of primary trial reports published from …
P Nevins, SG Nicholls, Y Ouyang, K Carroll… - BMJ open, 2022 - bmjopen.bmj.com
Objectives To describe the extent to which pragmatic trials underachieved or overachieved
their target sample sizes, examine explanations and identify characteristics associated with …
their target sample sizes, examine explanations and identify characteristics associated with …
Involving patients and the public In sTatistIcal Analysis pLans (INITIAL): A delphi survey
Background Patient and public involvement (PPI) in trials aims to enhance research by
improving its relevance and transparency. Planning for statistical analysis begins at the …
improving its relevance and transparency. Planning for statistical analysis begins at the …
“The power imbalance was blown out the window”: developing and implementing creative workshops to enhance communication of statistics in patient and public …
B Goulao, S Morisson - Research Involvement and Engagement, 2024 - Springer
Background Despite the importance of statistical and numerical aspects in key decisions
related to clinical trials and their impact in patient's care, patient and public involvement …
related to clinical trials and their impact in patient's care, patient and public involvement …
The role of progression criteria in the design, conduct, analysis and reporting of external randomised pilot trials
K Mellor - 2022 - ora.ox.ac.uk
External randomised pilot trials aim to assess whether a future definitive Randomised
Controlled Trial (RCT) is feasible. Prespecified progression criteria help guide the …
Controlled Trial (RCT) is feasible. Prespecified progression criteria help guide the …
地域精神保健福祉研究における患者・市民参画の研究段階および研究テーマに関する見解複数の立場の視点に基づく質的内容分析
川口敬之， 阿部真貴子， 山口創生， 五十嵐百花， 小川亮… - 医療と社会, 2023 - jstage.jst.go.jp
地域精神保健福祉研究における患者・市民参画の研究段階 および研究テーマに関する見解 Page 1
257 医療と社会 J Health Care Soc 33:257-270, 2023 doi:10.4091/iken. 2023. 001 地域精神保健 …
257 医療と社会 J Health Care Soc 33:257-270, 2023 doi:10.4091/iken. 2023. 001 地域精神保健 …