Effect of physical activity on risk of Alzheimer's disease: a systematic review and meta-analysis of twenty-nine prospective cohort studies

X Zhang, Q Li, W Cong, S Mu, R Zhan, S Zhong… - Ageing Research …, 2023 - Elsevier
Objective Physical activity (PA) is beneficial in reductions of all-cause mortality and
dementia. However, whether Alzheimer's disease (AD) risk is modified by PA remains …

Dietary protection against cognitive impairment, Neuroinflammation and oxidative stress in Alzheimer's disease animal models of lipopolysaccharide-induced …

D Decandia, F Gelfo, E Landolfo, F Balsamo… - International Journal of …, 2023 - mdpi.com
Alzheimer's disease (AD) is a rapidly growing epidemic with a heavy social and economic
burden. Evidence suggests that systemic inflammation, dysregulation of the immune …

Clinical evidence of human pathogens implicated in Alzheimer's disease pathology and the therapeutic efficacy of antimicrobials: An overview

CSG Catumbela, VV Giridharan, T Barichello… - Translational …, 2023 - Springer
A wealth of pre-clinical reports and data derived from human subjects and brain autopsies
suggest that microbial infections are relevant to Alzheimer's disease (AD). This has inspired …

[HTML][HTML] Associations of midlife dietary patterns with incident dementia and brain structure: findings from the UK biobank study

J Zhang, X Cao, X Li, X Li, M Hao, Y Xia… - The American journal of …, 2023 - Elsevier
Background At present, the results on the associations between dietary patterns and risk of
dementia are inconsistent, and studies on the associations between dietary patterns and …

Onset age of diabetes and incident dementia: A prospective cohort study

Y Wang, C Li, J Liang, D Gao, Y Pan, W Zhang… - Journal of Affective …, 2023 - Elsevier
Background Relationship between age at diagnosis of diabetes and dementia is lacking.
The aim of the study was to investigate whether diabetes onset at a younger age was …

Intrinsic Capacity, Polygenic Risk Score, APOE Genotype, and Risk of Dementia: A Prospective Cohort Study Based on the UK Biobank

M Sun, Q He, N Sun, Q Han, Y Wang, H Zhao, G Li… - Neurology, 2024 - AAN Enterprises
Background and Objectives The World Health Organization recently released a novel metric
for healthy aging: intrinsic capacity (IC). The relationship between IC and the incidence of …

Change in physical activity and systolic blood pressure trajectories throughout mid-life and the development of dementia in older age: the HUNT study

M Lerfald, S Lydersen, E Zotcheva, TIL Nilsen… - European Review of …, 2023 - Springer
Background There is lack of research on combinations of possible modifiable risk factors for
dementia in a life-time perspective. Dementia has currently no cure, and therefore new …

Treadmill running and Levisticum Officinale extract protect against LPS-induced memory deficits by modulating neurogenesis, neuroinflammation and oxidative stress

E Amraie, I Pouraboli, H Salehi, Z Rajaei - Metabolic Brain Disease, 2023 - Springer
Neuroinflammation plays an essential role in the pathogenesis of Alzheimer's disease. The
preventive effect of physical exercise on attenuating neuroinflammation has not been …

Association between probable sarcopenia and dementia risk: a prospective cohort study with mediation analysis

Y Ling, S Yuan, X Huang, S Tan, H Cheng, L Li… - Translational …, 2024 - nature.com
The role of alcohol consumption as a mediator in the risk between sarcopenia and dementia
remains inadequately studied. There is currently limited research on whether the association …

[HTML][HTML] The causality between leisure sedentary behaviors, physical activity and obstructive sleep apnea: a bidirectional Mendelian randomization study

H Tian, A Wang, H Wu, C Zhou, Z Zhang… - Frontiers in Public …, 2024 - frontiersin.org
Background Previous observational studies have shown a correlation between leisure
sedentary behaviors (LSB) and physical activity (PA) with the incidence of obstructive sleep …