A scoping review and meta-analysis of anti-CGRP monoclonal antibodies: predicting response

JB Hong, KS Lange, LH Overeem, P Triller, B Raffaelli… - Pharmaceuticals, 2023 - mdpi.com
Calcitonin gene-related peptide-targeted monoclonal antibodies (CGRP mAbs) are
increasingly being used as preventive treatments for migraine. Their effectiveness and …

New migraine prophylactic drugs: Current evidence and practical suggestions for non-responders to prior therapy

MJ Lee, MAM Al-Karagholi, U Reuter - Cephalalgia, 2023 - journals.sagepub.com
Background Monoclonal antibodies against calcitonin gene-related peptide (CGRP) or its
receptor (anti-CGRP (-R) mAbs) and small-molecule CGRP receptor antagonists (gepants) …

Predictors of response to anti-CGRP monoclonal antibodies: a 24-week, multicenter, prospective study on 864 migraine patients

P Barbanti, G Egeo, C Aurilia, C Altamura… - The Journal of …, 2022 - Springer
Background and objectives The identification of predictors of response to antiCGRP mAbs
could favor tailored therapies and personalized treatment plans. This study is aimed at …

Fremanezumab in the prevention of high-frequency episodic and chronic migraine: a 12-week, multicenter, real-life, cohort study (the FRIEND study)

P Barbanti, G Egeo, C Aurilia, F d'Onofrio… - The Journal of …, 2022 - Springer
Background Fremanezumab has demonstrated to be effective, safe, and tolerated in the
prevention of episodic or chronic migraine (CM) in randomized, placebo-controlled trials …

Long-term effectiveness of three anti-CGRP monoclonal antibodies in resistant chronic migraine patients based on the MIDAS score

LF Iannone, D Fattori, S Benemei, A Chiarugi… - CNS drugs, 2022 - Springer
Background Criteria, including clinical features and effective outcomes, for access and
persistence of novel but costly treatments may vary between countries, thus affecting the …

Real-world long-term efficacy and safety of erenumab in adults with chronic migraine: a 52-week, single-center, prospective, observational study

CK Cullum, TP Do, M Ashina, L Bendtsen… - The Journal of …, 2022 - Springer
Background Clinical trials have shown that erenumab is effective and well-tolerated for the
preventive treatment of chronic migraine. To extend the results from clinical trials, we …

Clinical evaluation of super-responders vs. non-responders to CGRP (-receptor) monoclonal antibodies: a real-world experience

B Raffaelli, M Fitzek, LH Overeem, E Storch… - The Journal of …, 2023 - Springer
Background Clinical trials and real-world studies revealed a spectrum of response to CGRP
(-receptor) monoclonal antibodies (mAbs) in migraine prophylaxis, ranging from no effect at …

Maintenance of response and predictive factors of 1‐year GalcanezumAb treatment in real‐life migraine patients in Italy: The multicenter prospective cohort GARLIT …

F Vernieri, N Brunelli, M Marcosano… - European Journal of …, 2023 - Wiley Online Library
Abstract Background and Purpose To evaluate the 1‐year effectiveness and tolerability of
galcanezumab in real life and the prognostic indicators of persistent response. Methods …

Discontinuing monoclonal antibodies targeting CGRP pathway after one-year treatment: an observational longitudinal cohort study

F Vernieri, N Brunelli, R Messina, CM Costa… - The Journal of …, 2021 - Springer
Background Monoclonal antibodies anti-calcitonin gene-related peptide (mAbs anti-CGRP)
pathway are effective and safe on migraine prevention. However, some drug agencies …

Monoclonal antibodies against calcitonin gene-related peptide for migraine prophylaxis: a systematic review of real-world data

AR Pavelic, C Wöber, F Riederer, K Zebenholzer - Cells, 2022 - mdpi.com
Objective: To perform a systematic review of real-world outcomes for anti-CGRP-mAbs.
Methods: Following the PRISMA guidelines, we searched PubMed for real-world data of …