The extracellular matrix (ECM) is an essential component of the heart that imparts
fundamental cellular processes during organ development and homeostasis. Most …

Myocardial infarction (MI) is a pathological process, evidencing as massive death of
cardiomyocytes associated with hypoxic and oxidative stress. The formation of areas of …

Cardiac remodelling mainly manifests as excessive myocardial hypertrophy and fibrosis,
which are associated with heart failure. Gentianella acuta (G. acuta) is reportedly effective in …

Severe cardiac remodeling leading to heart failure in individuals harboring pathogenic
LMNA variants, known as cardiolaminopathy, poses a significant clinical challenge …

Cardiovascular diseases (CVDs) are a major cause of death worldwide, leading to
increased medical care costs. To turn the scale, it is essential to acquire a more in-depth and …

Rationale: Cardiac fibrosis is an integral constituent of every form of chronic heart disease,
and persistence of fibrosis reduces tissue compliance and accelerates the progression to …

Hypertrophy cardiomyopathy (HCM) is the most common heritable cardiovascular disease
and often results in cardiac remodeling and an increased incidence of sudden cardiac arrest …

Background Acute lung injury (ALI) is a common complication following severe burns. The
underlying mechanisms of ALI are incompletely understood; thus, available treatments are …

Cardiac mesenchymal stem cells (C-MSCs) are a novel mesenchymal stem cell (MSC)
subpopulation derived from cardiac tissue, which are reported to be responsible for cardiac …

Myocardial fibrosis (MF) is an inevitable pathological process in the terminal stage of many
cardiovascular diseases, often leading to serious cardiac dysfunction and even death …