[HTML][HTML] Challenges for immunotherapy for the treatment of platinum resistant ovarian cancer
O Le Saux, I Ray-Coquard, SI Labidi-Galy - Seminars in cancer biology, 2021 - Elsevier
Platinum resistant ovarian cancer, usually defined as progression occurring within 6 months
after completing platinum-based therapy, is a heterogeneous disease with poor prognosis …
after completing platinum-based therapy, is a heterogeneous disease with poor prognosis …
Hippo signaling in the ovary: emerging roles in development, fertility, and disease
Emerging studies indicate that the Hippo pathway, a highly conserved pathway that
regulates organ size control, plays an important role in governing ovarian physiology …
regulates organ size control, plays an important role in governing ovarian physiology …
Neutrophil extracellular traps: a new player in cancer metastasis and therapeutic target
D Yang, J Liu - Journal of Experimental & Clinical Cancer Research, 2021 - Springer
Abstract Neutrophil Extracellular Traps (NETs) are neutrophil-derived extracellular scaffolds,
which typically consist of fibrous decondensed chromatins decorated with histones and …
which typically consist of fibrous decondensed chromatins decorated with histones and …
FOXM1: a multifunctional oncoprotein and emerging therapeutic target in ovarian cancer
Simple Summary Ovarian cancer is a lethal disease in women with a 10-year survival rate
of< 40% worldwide. A key molecular alteration in ovarian cancer is the aberrant …
of< 40% worldwide. A key molecular alteration in ovarian cancer is the aberrant …
Insights into the role of oxidative stress in ovarian cancer
DN Ding, LZ Xie, Y Shen, J Li, Y Guo… - Oxidative medicine …, 2021 - Wiley Online Library
Oxidative stress (OS) arises when the body is subjected to harmful endogenous or
exogenous factors that overwhelm the antioxidant system. There is increasing evidence that …
exogenous factors that overwhelm the antioxidant system. There is increasing evidence that …
Synthesis of quercetin functionalized wurtzite type zinc oxide nanoparticles and their potential to regulate intrinsic apoptosis signaling pathway in human metastatic …
V Ramalingam, PM Sathya, T Srivalli, H Mohan - Life Sciences, 2022 - Elsevier
In the present study, the wurtzite (WZ) type of zinc oxide (ZnO) nanoparticles were
synthesized and functionalized with quercetin (ZnO@ Quercetin) for the treatment of ovarian …
synthesized and functionalized with quercetin (ZnO@ Quercetin) for the treatment of ovarian …
Untargeted metabolomics analysis on kidney tissues from mice reveals potential hypoxia biomarkers
Chronic hypoxia may have a huge impact on the cardiovascular and renal systems.
Advancements in microscopy, metabolomics, and bioinformatics provide opportunities to …
Advancements in microscopy, metabolomics, and bioinformatics provide opportunities to …
TRAIL-dependent apoptosis of peritoneal mesothelial cells by NK cells promotes ovarian cancer invasion
AM Steitz, C Schröder, I Knuth, CU Keber… - Iscience, 2023 - cell.com
A crucial requirement for metastasis formation in ovarian high-grade serous carcinoma
(HGSC) is the disruption of the protective peritoneal mesothelium. Using co-culture systems …
(HGSC) is the disruption of the protective peritoneal mesothelium. Using co-culture systems …
L1CAM is required for early dissemination of fallopian tube carcinoma precursors to the ovary
Most ovarian high-grade serous carcinomas (HGSC) arise from Serous Tubal Intraepithelial
Carcinoma (STIC) lesions in the distal end of the fallopian tube (FT). Formation of STIC …
Carcinoma (STIC) lesions in the distal end of the fallopian tube (FT). Formation of STIC …
Cellular models of development of ovarian high‐grade serous carcinoma: A review of cell of origin and mechanisms of carcinogenesis
J Mei, H Tian, HS Huang, CF Hsu, Y Liou… - Cell …, 2021 - Wiley Online Library
High‐grade serous carcinoma (HGSC) is the most common and malignant histological type
of epithelial ovarian cancer, the origin of which remains controversial. Currently, the …
of epithelial ovarian cancer, the origin of which remains controversial. Currently, the …