Preparation and application of pH-responsive drug delivery systems
Microenvironment-responsive drug delivery systems (DDSs) can achieve targeted drug
delivery, reduce drug side effects and improve drug efficacies. Among them, pH-responsive …
delivery, reduce drug side effects and improve drug efficacies. Among them, pH-responsive …
[HTML][HTML] Insights on functionalized carbon nanotubes for cancer theranostics
L Tang, Q Xiao, Y Mei, S He, Z Zhang, R Wang… - Journal of …, 2021 - Springer
Despite the exciting breakthroughs in medical technology, cancer still accounts for one of
the principle triggers of death and conventional therapeutic modalities often fail to attain an …
the principle triggers of death and conventional therapeutic modalities often fail to attain an …
Magnetic‐Powered Janus Cell Robots Loaded with Oncolytic Adenovirus for Active and Targeted Virotherapy of Bladder Cancer
A unique robotic medical platform is designed by utilizing cell robots as the active “Trojan
horse” of oncolytic adenovirus (OA), capable of tumor‐selective binding and killing. The OA …
horse” of oncolytic adenovirus (OA), capable of tumor‐selective binding and killing. The OA …
[HTML][HTML] Targeting integrins for cancer therapy-disappointments and opportunities
C Bergonzini, K Kroese, AJM Zweemer… - Frontiers in Cell and …, 2022 - frontiersin.org
Integrins mediate adhesive interactions between cells and their environment, including
neighboring cells and extracellular matrix (ECM). These heterodimeric transmembrane …
neighboring cells and extracellular matrix (ECM). These heterodimeric transmembrane …
[HTML][HTML] Versatile carbon nanoplatforms for cancer treatment and diagnosis: strategies, applications and future perspectives
L Tang, J Li, T Pan, Y Yin, Y Mei, Q Xiao, R Wang… - Theranostics, 2022 - ncbi.nlm.nih.gov
Despite the encouraging breakthroughs in medical development, cancer remains one of the
principle causes of death and threatens human health around the world. Conventional …
principle causes of death and threatens human health around the world. Conventional …
Lipid nanocarrier-based drug delivery systems: therapeutic advances in the treatment of lung cancer
Although various treatments are currently being developed, lung cancer still has a very high
mortality rate. Moreover, while various strategies for the diagnosis and treatment of lung …
mortality rate. Moreover, while various strategies for the diagnosis and treatment of lung …
Nano-based targeted drug delivery for lung cancer: therapeutic avenues and challenges
D Ezhilarasan, T Lakshmi, SK Mallineni - Nanomedicine, 2022 - Taylor & Francis
Most anticancer drugs often fail in clinical trials due to poor solubility, poor bioavailability,
lack of targeted delivery and several off-target effects. Polymeric nanoparticles such as poly …
lack of targeted delivery and several off-target effects. Polymeric nanoparticles such as poly …
Effect of surface ligand modification on the properties of anti-tumor nanocarrier
N Ying, X Lin, M Xie, D Zeng - Colloids and Surfaces B: Biointerfaces, 2022 - Elsevier
With the continuous increasing number of cancer patients worldwide, there has been great
interest in developing the targeted delivery anti-cancer drugs. The drug concentration …
interest in developing the targeted delivery anti-cancer drugs. The drug concentration …
[HTML][HTML] Integrin β1 in pancreatic cancer: expressions, functions, and clinical implications
J Li, L Peng, Q Chen, Z Ye, T Zhao, S Hou, J Gu… - Cancers, 2022 - mdpi.com
Simple Summary Pancreatic cancer (PC) is a highly aggressive malignant tumor with an
extremely poor prognosis. Early diagnosis and treatment are key to improving the survival …
extremely poor prognosis. Early diagnosis and treatment are key to improving the survival …
[HTML][HTML] Dual stimuli-responsive mesoporous silica nanoparticles for efficient loading and smart delivery of doxorubicin to cancer with RGD-integrin targeting
The recent progress in nanoparticle applications, such as tumor-targeting, has enabled
specific delivery of chemotherapeutics to malignant tissues with enhanced local efficacy …
specific delivery of chemotherapeutics to malignant tissues with enhanced local efficacy …