Chronic pain affects a large part of the population causing functional disability, being often
associated with coexisting psychological disorders, such as depression and anxiety …

Simple Summary It is crucial that research primates receive adequate pain treatment from
ethical, animal welfare, and research-related perspectives. There is limited research on …

Chronic musculoskeletal (MSK) pain is disabling to individuals and burdensome to society.
A relationship between telomere length and resilience was reported in individuals with …

Neuropathic pain is often accompanied by anxiety and depression-like manifestations. Many
studies have shown that alterations in synaptic plasticity in the anterior cingulate cortex …

Ever since Le Bars et al. 21 detailed in 1979 that “the activity of convergent dorsal horn
neurons could be powerfully inhibited by noxious stimuli applied to various parts of the …

Descending control of nociception (DCN; also known as conditioned pain modulation [CPM],
the behavioral correlate of diffuse noxious inhibitory controls) is the phenomenon whereby …

Temporomandibular disorder (TMD) and irritable bowel syndrome (IBS) are 2 chronic
overlapping pain conditions (COPCs) that present with significant comorbidity. Both …

Chronic pain is one of the most challenging and debilitating symptoms to manage after
traumatic brain injury (TBI), yet the underlying mechanisms remain elusive. The disruption of …

Old age and female sex are risk factors for the development of osteoarthritis (OA) and
chronic pain. We investigated the effects of sex and age on pain modulatory networks in a …

People living with pain report drinking alcohol to relieve pain. Acute alcohol use reduces
pain, and chronic alcohol use facilitates the emergence or exaggeration of pain. Recently …