Chronic pain in the elderly: mechanisms and perspectives
APA Dagnino, MM Campos - Frontiers in Human Neuroscience, 2022 - frontiersin.org
Chronic pain affects a large part of the population causing functional disability, being often
associated with coexisting psychological disorders, such as depression and anxiety …
associated with coexisting psychological disorders, such as depression and anxiety …
Challenges with assessing and treating pain in research primates: A focused survey and literature review
EA Paterson, PV Turner - Animals, 2022 - mdpi.com
Simple Summary It is crucial that research primates receive adequate pain treatment from
ethical, animal welfare, and research-related perspectives. There is limited research on …
ethical, animal welfare, and research-related perspectives. There is limited research on …
Resilience, pain, and the brain: Relationships differ by sociodemographics
Chronic musculoskeletal (MSK) pain is disabling to individuals and burdensome to society.
A relationship between telomere length and resilience was reported in individuals with …
A relationship between telomere length and resilience was reported in individuals with …
The cAMP response element-binding protein/brain-derived neurotrophic factor pathway in anterior cingulate cortex regulates neuropathic pain and Anxiodepression …
J Wen, Y Xu, Z Yu, Y Zhou, W Wang, J Yang… - Frontiers in Molecular …, 2022 - frontiersin.org
Neuropathic pain is often accompanied by anxiety and depression-like manifestations. Many
studies have shown that alterations in synaptic plasticity in the anterior cingulate cortex …
studies have shown that alterations in synaptic plasticity in the anterior cingulate cortex …
Introducing descending control of nociception: a measure of diffuse noxious inhibitory controls in conscious animals
Ever since Le Bars et al. 21 detailed in 1979 that “the activity of convergent dorsal horn
neurons could be powerfully inhibited by noxious stimuli applied to various parts of the …
neurons could be powerfully inhibited by noxious stimuli applied to various parts of the …
Monoaminergic mediation of hyperalgesic and analgesic descending control of nociception in mice
Descending control of nociception (DCN; also known as conditioned pain modulation [CPM],
the behavioral correlate of diffuse noxious inhibitory controls) is the phenomenon whereby …
the behavioral correlate of diffuse noxious inhibitory controls) is the phenomenon whereby …
[HTML][HTML] Sex differences in visceral sensitivity and brain activity in a rat model of comorbid pain: a longitudinal study
Temporomandibular disorder (TMD) and irritable bowel syndrome (IBS) are 2 chronic
overlapping pain conditions (COPCs) that present with significant comorbidity. Both …
overlapping pain conditions (COPCs) that present with significant comorbidity. Both …
Loss of diffuse noxious inhibitory control after traumatic brain injury in rats: a chronic issue
KA Irvine, P Sahbaie, AR Ferguson, JD Clark - Experimental Neurology, 2020 - Elsevier
Chronic pain is one of the most challenging and debilitating symptoms to manage after
traumatic brain injury (TBI), yet the underlying mechanisms remain elusive. The disruption of …
traumatic brain injury (TBI), yet the underlying mechanisms remain elusive. The disruption of …
Pain modulatory network is influenced by sex and age in a healthy state and during osteoarthritis progression in rats
JT Da Silva, C Tricou, Y Zhang, A Tofighbakhsh… - Aging …, 2021 - Wiley Online Library
Old age and female sex are risk factors for the development of osteoarthritis (OA) and
chronic pain. We investigated the effects of sex and age on pain modulatory networks in a …
chronic pain. We investigated the effects of sex and age on pain modulatory networks in a …
[HTML][HTML] Forebrain-midbrain circuits and peptides involved in hyperalgesia after chronic alcohol exposure
People living with pain report drinking alcohol to relieve pain. Acute alcohol use reduces
pain, and chronic alcohol use facilitates the emergence or exaggeration of pain. Recently …
pain, and chronic alcohol use facilitates the emergence or exaggeration of pain. Recently …