Cell-free circulating DNA (cfDNA) in plasma has gained global interest as a diagnostic
material for noninvasive prenatal testing and cancer diagnosis, or the so-called “liquid …

Early detection has the potential to reduce cancer mortality, but an effective screening test
must demonstrate asymptomatic cancer detection years before conventional diagnosis in a …

Abstract N6-methyladenosine (m6A) serves as a major RNA methylation modification and
impacts the initiation and progression of various human cancers through diverse …

Non-small-cell lung cancer (NSCLC), the most common type of lung cancer accounting for
85% of the cases, is often diagnosed at advanced stages owing to the lack of efficient early …

Simple Summary Malignant liver tumors consist of primary tumors and metastases. A correct
diagnosis can be achieved with different methods; one of them is the analysis of the cell-free …

Cancer is the second leading cause of death worldwide being responsible for 9.6 million
deaths in 2018. Epigenetic alterations are key in directing the aberrant expression of tumor …

Ovarian cancer is a highly heterogeneous disease and its formation is affected by many
epidemiological factors. It has typical lack of early signs and symptoms, and almost 70% of …

Introduction Lung cancer (LC) is the leading cause of death from cancer. Early diagnosis of
LC is of paramount importance in terms of prognosis. The health authorities of most …

The practice of liquid biopsy (LB) has revolutionized the care of patients with metastatic lung
cancer. Many oncologists now use this approach in daily practice, applying precise …

Innovative diagnostics are becoming an essential component in personalized cancer
medicine. These diagnostics are increasingly based on cell-free nucleic acids and …