Endogenous pain regulatory system dysfunction appears to play a role in the maintenance
of chronic pain. An important component of the pain regulatory process is the functional …

A behavioral hypalgesia (increased response threshold to noxious stimuli) has been
consistently, although not invariably, reported in spontaneous and experimental acute and …

Objective This article examines possible sources of heightened psychophysiological
reactivity in relation to risk for hypertension and coronary artery disease. The idea that …

A meta-analysis of 295 relevant effect sizes obtained from 25,469 participants confirmed
expectations that elevated blood pressure (BP) and essential hypertension (EH) would be …

Objective The purpose of this study was to determine race and sex differences in cutaneous
pain perception. Methods Pain perception was measured using a suprathreshold evaluation …

Previously reported differences in sensitivity to experimental pain stimuli between the sexes,
as well as between temporomandibular disorder (TMD) patients and healthy control …

Background: Chronic pelvic pain (CPP) is a complex pain syndrome. Since its pathogenesis
is still poorly understood and structural alterations in pain related brain regions may be …

Recent research suggests that resting blood pressure is inversely related to pain sensitivity,
even among normotensives; however, most of these studies have included only male …

Objectives: In healthy individuals, elevated blood pressure is associated with diminished
acute pain sensitivity. These cardiovascular/pain regulatory system interactions appear …

A series of studies was undertaken to determine whether CO2 can be used as a humane as
well as practical agent for euthanasia or anesthesia of rats. Human volunteers rated the …