Ionizing radiation and its effects on pharmaceuticals

ET Sarcan, AY Ozer - Journal of Radioanalytical and Nuclear Chemistry, 2020 - Springer
Radiation is used for different purposes such as sterilization, imaging, analysis and security.
Sterilization, one of the the using area of radiation, is important issue for industries. The …

[HTML][HTML] Formulation and characterization of EGCG for the treatment of superficial bladder cancer

K Dettlaff, M Stawny… - International …, 2017 - spandidos-publications.com
Abstract In the United States, the annual incidence of bladder cancer is approximately
70,000 new cases, with a mortality rate of approximately 15,000/year. The most common …

The influence of radiation sterilisation on some β-blockers in the solid state

B Marciniec, M Ogrodowczyk, B Czajka, M Hofman - Thermochimica acta, 2011 - Elsevier
Six derivatives of aryloxyalkylaminopropanol of known β-adrenolytic activity (acebutolol,
alprenolol, atenolol, metoprolol, pindolol, propranolol) in solid phase were exposed to the …

Green technology for salt formation: slurry reactive crystallization studies for papaverine HCl and 1: 1 haloperidol–maleic acid salt

JD Damayanti, DE Pratama, T Lee - Crystal Growth & Design, 2019 - ACS Publications
Papaverine HCl was successfully suspended by slurry reactive crystallization with the use of
isopropyl alcohol (IPA) at 25° C, a solid-to-liquid ratio of 0.19 g/mL, an aging time of 8 h, a …

The radiolytic studies of cefpirome sulfate in the solid state

P Zalewski, R Skibiński… - … of Pharmaceutical and …, 2016 - Elsevier
The possibility of applying radiation sterilization to cefpirome sulfate was investigated. The
lack of changes in the chemical structure of cefpirome sulfate irradiated with a dose of 25 …

[HTML][HTML] Analytical study on irradiated methylxanthine derivatives

B Marciniec, M Stawny, K Olszewski, M Kozak… - Journal of thermal …, 2013 - Springer
The effect of ionising radiation on the physico-chemical properties of three derivatives of
xanthine: caffeine, theophylline and theobromine, has been studied. The above-drugs in the …

[HTML][HTML] DSC and spectroscopic studies of disulfiram radiostability in the solid state

B Marciniec, K Dettlaff, M Naskrent… - Journal of thermal …, 2012 - akjournals.com
The effect of ionising radiation on the physico-chemical properties of disulfiram (Antabuse,
Esperal, bisdiethylthiocarbamoil disulphide) has been studied by DSC, FTIR, EPR, MS, TLC …

Radiostability of ketoconazole in the solid state

B Marciniec, K Dettlaff, W Danikiewicz… - Current …, 2013 - ingentaconnect.com
Ketoconazole (1-[4-(4-{[(2R, 4S)-2-(2, 4-dichlorophenyl)-2-(1H-imidazol-1-ylmethyl)-1, 3-
dioxolan-4-yl]-methoxy} phenyl) piperazin-1-yl] ethan-1-one) in substantia was irradiated to …

THE ROLE OF PHARMACEUTICAL ANALYSIS IN ENSURING THE SAFETY OF DRUG RADIATION STERILIZATION.

A KACZMAREK, M OGRODOWCZYK… - Acta Poloniae …, 2023 - search.ebscohost.com
Radiation sterilization is a widely used method for ensuring the sterility of medical and
pharmaceutical products. The process involves exposing the products to ionizing radiation …

[PDF][PDF] The effect of excipients on the release kinetics of diclofenac sodium and papaverine hydrochloride from composed tablets

R Kasperek, HTR BACZ, Ł Zimmer… - Acta Poloniae …, 2014 - ptfarm.pl
For increased analgesic effect, new composed tablets containing diclofenac sodium (DIC)
with an addition of papaverine hydrochloride (PAP) were prepared to investigate the …