Nanoplatform-based cascade engineering for cancer therapy

J Chen, Y Zhu, C Wu, J Shi - Chemical Society Reviews, 2020 - pubs.rsc.org
Various therapeutic techniques have been studied for treating cancer precisely and
effectively, such as targeted drug delivery, phototherapy, tumor-specific catalytic therapy …

Modulating glycolysis to improve cancer therapy

C Chelakkot, VS Chelakkot, Y Shin, K Song - International Journal of …, 2023 - mdpi.com
Cancer cells undergo metabolic reprogramming and switch to a 'glycolysis-
dominant'metabolic profile to promote their survival and meet their requirements for energy …

Simultaneous Fenton‐like Ion Delivery and Glutathione Depletion by MnO2‐Based Nanoagent to Enhance Chemodynamic Therapy

LS Lin, J Song, L Song, K Ke, Y Liu, Z Zhou… - Angewandte …, 2018 - Wiley Online Library
Chemodynamic therapy (CDT) utilizes iron‐initiated Fenton chemistry to destroy tumor cells
by converting endogenous H2O2 into the highly toxic hydroxyl radical (. OH). There is a …

[PDF][PDF] Cascading of Molecular Logic Gates for Advanced Functions: A Self‐Reporting, Activatable Photosensitizer

S Erbas‐Cakmak, EU Akkaya - Angewandte Chemie, 2013 - yoksis.bilkent.edu.tr
The complexity of biochemical reaction networks usually arises from the cascade of
reactions that control or are controlled by other reactions in the network. This enables signal …

[HTML][HTML] Nanoplatforms for targeted stimuli-responsive drug delivery: a review of platform materials and stimuli-responsive release and targeting mechanisms

Y Sun, E Davis - Nanomaterials, 2021 - mdpi.com
To achieve the promise of stimuli-responsive drug delivery systems for the treatment of
cancer, they should (1) avoid premature clearance;(2) accumulate in tumors and undergo …

Combination of photodynamic therapy with anti-cancer agents

MF Zuluaga, N Lange - Current medicinal chemistry, 2008 - ingentaconnect.com
Degenerative diseases such as cancer usually involve more than one pathological process.
Therefore, attempts to combat such diseases with monotherapeutic approaches may not …

Photosensitizers for Photodynamic Therapy of Brain Cancers—A Review

D Bartusik-Aebisher, P Woźnicki, K Dynarowicz… - Brain Sciences, 2023 - mdpi.com
On average, there are about 300,000 new cases of brain cancer each year. Studies have
shown that brain and central nervous system tumors are among the top ten causes of death …

Barriers to carrier mediated drug and gene delivery to brain tumors

GH Huynh, DF Deen, FC Szoka Jr - Journal of Controlled Release, 2006 - Elsevier
Brain tumor patients face a poor prognosis despite significant advances in tumor imaging,
neurosurgery and radiation therapy. Potent chemotherapeutic drugs fail when used to treat …

Optimal light dose for interstitial photodynamic therapy in treatment for malignant brain tumors

S Krishnamurthy, SK Powers, P Witmer… - Lasers in Surgery and …, 2000 - Wiley Online Library
Abstract Background and Objective The primary goal was to determine the maximal
tolerable light dose that can be administered to patients undergoing multifiber interstitial …

MnO2 Nanozyme‐Loaded MXene for Cancer Synergistic Photothermal‐Chemodynamic Therapy

J Li, X Cai, Y Zhang, K Li, L Guan, Y Li… - …, 2022 - Wiley Online Library
Nanozymes, as an emerging representative of nanocatalytic technology, have recently been
widely used in the treatment of tumors. However, considering the limitation of the tumor …