Cryo-electron microscopy (CryoEM) has become a vital technique in structural biology. It is
an interdisciplinary field that takes advantage of advances in biochemistry, physics, and …

Biocatalysis has become an indispensable tool for modern organic synthesis, both in
academia and across pharmaceutical and chemical industries. In the past decade, new …

In a surprisingly short time, electron cryo-microscopy (cryoEM) has developed from a niche
technique in structural biology to a mainstream method practiced in a rapidly growing …

In rod photoreceptors of the retina, the cyclic nucleotide-gated (CNG) channel is composed
of three CNGA and one CNGB subunits, and it closes in response to light activation to …

One of the key goals in single-particle cryo-microscopy is to obtain a uniform distribution of
particle orientations, so that the three-dimensional structure has isotropic resolution in …

We present a process for the manufacture of electron cryomicroscopy (cryoEM) specimen
supports with an integrated foil–grid structure, using cryogenic vacuum evaporation …

We report the first bioconjugation of Au25 nanocluster to a monoclonal antibody at scarcely
exposed tryptophan (Trp) residues toward the development of high-resolution probes for …

The availability of atomic resolution experimental maps of electrostatic potential from 3D
electron diffraction (3D ED) extends the possibility of investigating the electrostatic potential …

Deciphering the three-dimensional structures of macromolecules is of paramount
importance for gaining insights into their functions and roles in human health and disease …

We consider thetwo-dimensional multi-target detection problem of recovering a target image
from a noisy measurement that contains multiple copies of the image, each randomly rotated …