Renal-protective roles of lipoic acid in kidney disease

SF Kamt, J Liu, LJ Yan - Nutrients, 2023 - mdpi.com
The kidney is a crucial organ that eliminates metabolic waste and reabsorbs nutritious
elements. It also participates in the regulation of blood pressure, maintenance of electrolyte …

Membranous nephropathy: systems biology-based novel mechanism and traditional Chinese medicine therapy

H Miao, Y Zhang, X Yu, L Zou, Y Zhao - Frontiers in pharmacology, 2022 - frontiersin.org
Membranous nephropathy (MN) is a renal-limited non-inflammatory autoimmune disease in
the glomerulus, which is the second or third main cause of end-stage kidney diseases in …

Clinical applications of plasma proteomics and peptidomics: Towards precision medicine

B He, Z Huang, C Huang… - PROTEOMICS–Clinical …, 2022 - Wiley Online Library
In the context of precision medicine, disease treatment requires individualized strategies
based on the underlying molecular characteristics to overcome therapeutic challenges …

The role of renal macrophage, AIM, and TGF-β1 expression in renal fibrosis progression in IgAN patients

M Yang, JW Liu, YT Zhang, G Wu - Frontiers in immunology, 2021 - frontiersin.org
Objective To analyze the expression of macrophages, AIM, TGF-β1 in the kidney of IgAN
patients, and to explore the role of macrophages, AIM, TGF-β1 in the progression of renal …

Endoglin is an important mediator in the final common pathway of chronic kidney disease to end-stage renal disease

T Gerrits, IJ Brouwer, KL Dijkstra, R Wolterbeek… - International Journal of …, 2022 - mdpi.com
Chronic kidney disease (CKD) is a slow-developing, progressive deterioration of renal
function. The final common pathway in the pathophysiology of CKD involves glomerular …

[HTML][HTML] Serum and urine metabolomic biomarkers for predicting prognosis in patients with immunoglobulin A nephropathy

YH Jeon, S Lee, S Kim, SS Bae, M Han… - Kidney Research and …, 2023 - ncbi.nlm.nih.gov
Background Immunoglobulin A nephropathy (IgAN) is the most prevalent form of
glomerulonephritis worldwide. Prediction of disease progression in IgAN can help to provide …

Rhein protects 5/6 nephrectomized rat against renal injury by reducing inflammation via NF-κB signaling

M Liu, L Wang, X Wu, K Gao, F Wang, J Cui… - … Urology and Nephrology, 2021 - Springer
Abstract Background/Aims Inflammation is well known to play a pivotal role in renal injury.
Rhein is a major component of the medicinal Rhubarb. The aim of this study was to …

Potential biomarkers and signaling pathways associated with the pathogenesis of primary ameloblastoma: a systems biology approach

Z Bayat, A Mirzaeian… - International Journal of …, 2022 - Wiley Online Library
Objective. Ameloblastoma is a benign odontogenic tumor that may lead to ameloblastic
carcinoma. This study aimed to determine potential signaling pathways and biological …

Analysis of the alleviating effect of modified Huangqi Chifeng decoction on rats with focal segmental glomerulosclerosis based on gut microbiota and fecal …

X Shi, Y Zhang, Y Shi, Q Zhang, H Duan… - Journal of Applied …, 2023 - academic.oup.com
Aims To investigate the reno-protective effects of modified Huangqi Chifeng decoction
(MHCD) on focal segmental glomerulosclerosis (FSGS) rats, and the underlying …

AZGP1 as a potential biomarker of IgA vasculitis with nephritis in a children‑based urinary proteomics study by diaPASEF

ZQ Zhu, T Zhang, S Chang… - Molecular Medicine …, 2023 - spandidos-publications.com
The present study aimed to screen for potential biomarkers in the urine of immunoglobulin A
vasculitis with nephritis (IgAVN) using parallel accumulation‑serial fragmentation combined …