Voltage-gated sodium channels (NaV) in GtoPdb v.2021.3

WA Catterall, AL Goldin… - IUPHAR/BPS Guide to …, 2021 - journals.ed.ac.uk
Sodium channels are voltage-gated sodium-selective ion channels present in the
membrane of most excitable cells. Sodium channels comprise of one pore-forming α …

Pain and analgesia: Mutations of voltage-gated sodium channels

MJ Eberhardt, A Leffler - Der Schmerz, 2017 - Springer
Spannungsabhängige Natriumkanäle (Nav) sind für die Generierung und Weiterleitung von
Aktionspotentialen in erregbaren Zellen, und somit auch für die Funktion sensibler Nerven …

Office-based anesthetic and oral surgical management of a child with hereditary sensory autonomic neuropathy type IV: A Case Report

S Prabhu, K Fortier, L Newsome… - Anesthesia …, 2018 - meridian.allenpress.com
Hereditary sensory and autonomic neuropathy type IV (HSAN IV), or congenital insensitivity
to pain with anhidrosis, is an exceptionally rare genetic disorder that results in the complete …

Trigeminal Neuralgia: Channels, Pathophysiology, and Therapeutic Challenges

D Cazzato, S Maarbjerg, L Bendtsen… - Cluster Headache and …, 2020 - Springer
Trigeminal neuralgia (TN) is a condition characterized by paroxysmal excruciating and
usually unilateral pain attacks within the territory of one or more divisions of the trigeminal …

Sensory and autonomic neuropathies and pain-related channelopathies

I Kurth - Der Schmerz, 2015 - Springer
Zusammenfassung Ein Verlust von Sensibilität und Schmerzempfinden kann durch einen
Entwicklungsdefekt, die Degeneration nozizeptiver Fasern oder eine veränderte neuronale …

Genetics meets function in sodium channel-related pain disorders

J Körner, N Haag, I Kurth, A Lampert - Neuroforum, 2022 - degruyter.com
Voltage-gated sodium channels are crucial for pain perception. This is illustrated by several
human genetic conditions that lead to either chronic pain or, vice versa, to congenital …

Establishing the zebrafish as a model to study the genetics of nociception

EDSCEV Clemente - 2022 - discovery.ucl.ac.uk
Pain is crucial for survival, and the ability to detect potentially harmful stimuli and respond
accordingly is evolutionarily conserved. However, pain can also be undesirable in several …

[引用][C] WNK1 基因突变导致Ⅱ 型遗传性感觉和自主神经病一家系

高利红, 李珊珊, 傅文贞, 章振林 - 中华内科杂志, 2016

Gene und Schmerz

C Sommer, K Doppler - Aktuelle Neurologie, 2016 - thieme-connect.com
Zur Genetik von Schmerzerkrankungen hat es in den letzten Jahren beträchtliche
Fortschritte gegeben. Diese betreffen zum einen monogenetische Erkrankungen, die mit …

The coexistence of a novel WNK1 variant and a copy number variation causes hereditary sensory and autonomic neuropathy type IIA

JJ Wang, B Yu, Z Li - BMC Medical Genetics, 2019 - Springer
Background Hereditary sensory and autonomic neuropathy (HSAN) type II is a group of
extremely rare autosomal recessive neurological disorders with heterogeneous clinical and …