Basal forebrain cholinergic signalling: development, connectivity and roles in cognition
MR Ananth, P Rajebhosale, R Kim… - Nature Reviews …, 2023 - nature.com
Acetylcholine plays an essential role in fundamental aspects of cognition. Studies that have
mapped the activity and functional connectivity of cholinergic neurons have shown that the …
mapped the activity and functional connectivity of cholinergic neurons have shown that the …
Role of calcium modulation in the pathophysiology and treatment of Alzheimer's disease
D Baracaldo-Santamaría, SS Avendaño-Lopez… - International journal of …, 2023 - mdpi.com
Alzheimer's disease (AD) is a chronic neurodegenerative disease and the most frequent
cause of progressive dementia in senior adults. It is characterized by memory loss and …
cause of progressive dementia in senior adults. It is characterized by memory loss and …
Heart-brain connections: Phenotypic and genetic insights from magnetic resonance images
Cardiovascular health interacts with cognitive and mental health in complex ways, yet little is
known about the phenotypic and genetic links of heart-brain systems. We quantified heart …
known about the phenotypic and genetic links of heart-brain systems. We quantified heart …
New perspectives on the basal forebrain cholinergic system in Alzheimer's disease
AS Berry, TM Harrison - Neuroscience & Biobehavioral Reviews, 2023 - Elsevier
The basal forebrain cholinergic system (BFCS) has long been implicated in age-related
cognitive changes and the pathophysiology of Alzheimer's disease (AD). Limitations of …
cognitive changes and the pathophysiology of Alzheimer's disease (AD). Limitations of …
[HTML][HTML] Structural Degeneration of the Nucleus basalis of Meynert in Mild Cognitive Impairment and Alzheimer's Disease–Evidence from an MRI-based Meta-Analysis
M Mieling, H Meier, N Bunzeck - Neuroscience & Biobehavioral Reviews, 2023 - Elsevier
Recent models of Alzheimer's Disease (AD) suggest that neuropathological changes of the
medial temporal lobe, especially entorhinal cortex, are preceded by degenerations of the …
medial temporal lobe, especially entorhinal cortex, are preceded by degenerations of the …
Targeting the M1 muscarinic acetylcholine receptor in Alzheimer's disease
Alzheimer's disease (AD) remains a major cause of morbidity and mortality worldwide, and
despite extensive research, only a few drugs are available for management of the disease …
despite extensive research, only a few drugs are available for management of the disease …
α7 nicotinic acetylcholine receptors in the hippocampal circuit: taming complexity
AC Letsinger, Z Gu, JL Yakel - Trends in neurosciences, 2022 - cell.com
Cholinergic innervation of the hippocampus uses the neurotransmitter acetylcholine (ACh)
to coordinate neuronal circuit activity while simultaneously influencing the function of non …
to coordinate neuronal circuit activity while simultaneously influencing the function of non …
Structural (dys) connectivity associates with cholinergic cell density in Alzheimer's disease
CP Lin, I Frigerio, BDC Boon, Z Zhou, AJM Rozemuller… - Brain, 2022 - academic.oup.com
Cognitive deficits in Alzheimer's disease, specifically amnestic (memory dominant) deficits,
are associated with cholinergic degeneration in the basal forebrain. The cholinergic nucleus …
are associated with cholinergic degeneration in the basal forebrain. The cholinergic nucleus …
The brilliance of the zebrafish model: perception on behavior and Alzheimer's disease
A Shenoy, M Banerjee, A Upadhya… - Frontiers in …, 2022 - frontiersin.org
Alzheimer's disease (AD) has become increasingly prevalent in the elderly population
across the world. It's pathophysiological markers such as overproduction along with the …
across the world. It's pathophysiological markers such as overproduction along with the …
The nerve growth factor metabolic pathway dysregulation as cause of Alzheimer's cholinergic atrophy
S Do Carmo, B Kannel, AC Cuello - Cells, 2021 - mdpi.com
The cause of the loss of basal forebrain cholinergic neurons (BFCNs) and their terminal
synapses in the cerebral cortex and hippocampus in Alzheimer's disease (AD) has provoked …
synapses in the cerebral cortex and hippocampus in Alzheimer's disease (AD) has provoked …