[HTML][HTML] Intrinsically disordered proteins: an overview

R Trivedi, HA Nagarajaram - International journal of molecular sciences, 2022 - mdpi.com
Many proteins and protein segments cannot attain a single stable three-dimensional
structure under physiological conditions; instead, they adopt multiple interconverting …

Protein language: post-translational modifications talking to each other

L Dai Vu, K Gevaert, I De Smet - Trends in plant science, 2018 - cell.com
Post-translational modifications (PTMs) are at the heart of many cellular signaling events.
Apart from a single regulatory PTM, there are also PTMs that function in orchestrated …

MobiDB: intrinsically disordered proteins in 2021

D Piovesan, M Necci, N Escobedo… - Nucleic acids …, 2021 - academic.oup.com
The MobiDB database (URL: https://mobidb. org/) provides predictions and annotations for
intrinsically disordered proteins. Here, we report recent developments implemented in …

15 years of PhosphoSitePlus®: integrating post-translationally modified sites, disease variants and isoforms

PV Hornbeck, JM Kornhauser, V Latham… - Nucleic acids …, 2019 - academic.oup.com
For 15 years the mission of PhosphoSitePlus®(PSP, https://www. phosphosite. org) has
been to provide comprehensive information and tools for the study of mammalian post …

CD36 as a gatekeeper of myocardial lipid metabolism and therapeutic target for metabolic disease

JFC Glatz, LC Heather… - Physiological reviews, 2024 - journals.physiology.org
The multifunctional membrane glycoprotein CD36 is expressed in different types of cells and
plays a key regulatory role in cellular lipid metabolism, especially in cardiac muscle. CD36 …

[HTML][HTML] The human SLC1A5 (ASCT2) amino acid transporter: from function to structure and role in cell biology

M Scalise, L Pochini, L Console, MA Losso… - Frontiers in cell and …, 2018 - frontiersin.org
SLC1A5, known as ASCT2, is a neutral amino acid transporter belonging to the SLC1 family
and localized in the plasma membrane of several body districts. ASCT2 is an acronym …

dbPTM in 2019: exploring disease association and cross-talk of post-translational modifications

KY Huang, TY Lee, HJ Kao, CT Ma, CC Lee… - Nucleic acids …, 2019 - academic.oup.com
Abstract The dbPTM (http://dbPTM. mbc. nctu. edu. tw/) has been maintained for over 10
years with the aim to provide functional and structural analyses for post-translational …

Multiple modes of protein–protein interactions promote RNP granule assembly

T Mittag, R Parker - Journal of molecular biology, 2018 - Elsevier
Eukaryotic cells are known to contain a wide variety of RNA–protein assemblies, collectively
referred to as RNP granules. RNP granules form from a combination of RNA–RNA, protein …

[HTML][HTML] Lactylation, an emerging hallmark of metabolic reprogramming: Current progress and open challenges

X Liu, Y Zhang, W Li, X Zhou - Frontiers in cell and developmental …, 2022 - frontiersin.org
Lactate, the end product of glycolysis, efficiently functions as the carbon source, signaling
molecules and immune regulators. Lactylation, being regulated by lactate, has recently been …

[HTML][HTML] An advanced strategy for comprehensive profiling of ADP-ribosylation sites using mass spectrometry-based proteomics

IA Hendriks, SC Larsen, ML Nielsen - Molecular & Cellular Proteomics, 2019 - ASBMB
ADP-ribosylation is a widespread post-translational modification (PTM) with crucial functions
in many cellular processes. Here, we describe an in-depth ADP-ribosylome using our …