Advancing biomaterials of human origin for tissue engineering
FM Chen, X Liu - Progress in polymer science, 2016 - Elsevier
Biomaterials have played an increasingly prominent role in the success of biomedical
devices and in the development of tissue engineering, which seeks to unlock the …
devices and in the development of tissue engineering, which seeks to unlock the …
Interactions between hyaluronan and its receptors (CD44, RHAMM) regulate the activities of inflammation and cancer
S Misra, VC Hascall, RR Markwald… - Frontiers in …, 2015 - frontiersin.org
The glycosaminoglycan hyaluronan (HA), a major component of extracellular matrices, and
cell surface receptors of HA have been proposed to have pivotal roles in cell proliferation …
cell surface receptors of HA have been proposed to have pivotal roles in cell proliferation …
Therapy resistance mediated by cancer stem cells
TB Steinbichler, J Dudás, S Skvortsov… - Seminars in cancer …, 2018 - Elsevier
Cancer stem cells (CSC) possess abilities generally associated with embryonic or adult
stem cells, especially self-renewal and differentiation. The CSC model assumes that this …
stem cells, especially self-renewal and differentiation. The CSC model assumes that this …
[HTML][HTML] Extracellular matrix: a dynamic microenvironment for stem cell niche
F Gattazzo, A Urciuolo, P Bonaldo - Biochimica et Biophysica Acta (BBA) …, 2014 - Elsevier
Background Extracellular matrix (ECM) is a dynamic and complex environment
characterized by biophysical, mechanical and biochemical properties specific for each …
characterized by biophysical, mechanical and biochemical properties specific for each …
The extracellular matrix: a dynamic niche in cancer progression
The local microenvironment, or niche, of a cancer cell plays important roles in cancer
development. A major component of the niche is the extracellular matrix (ECM), a complex …
development. A major component of the niche is the extracellular matrix (ECM), a complex …
Stem cell homing: From physiology to therapeutics
JL Liesveld, N Sharma, OS Aljitawi - Stem Cells, 2020 - academic.oup.com
Stem cell homing is a multistep endogenous physiologic process that is also used by
exogenously administered hematopoietic stem and progenitor cells (HSPCs). This multistep …
exogenously administered hematopoietic stem and progenitor cells (HSPCs). This multistep …
The physical and biochemical properties of the extracellular matrix regulate cell fate
The extracellular matrix is a complex network of hydrated macromolecular proteins and
sugars that, in concert with bound soluble factors, comprise the acellular stromal …
sugars that, in concert with bound soluble factors, comprise the acellular stromal …
Recent advances in metal‐phenolic networks for cancer theranostics
Nanomedicine integrates different functional materials to realize the customization of
carriers, aiming at increasing the cancer therapeutic efficacy and reducing the off‐target …
carriers, aiming at increasing the cancer therapeutic efficacy and reducing the off‐target …
CD44: can a cancer-initiating cell profit from an abundantly expressed molecule?
M Zöller - Nature Reviews Cancer, 2011 - nature.com
Can an abundantly expressed molecule be a reliable marker for the cancer-initiating cells
(CICs; also known as cancer stem cells), which constitute the minority of cells within the …
(CICs; also known as cancer stem cells), which constitute the minority of cells within the …
Hyaluronan as an immune regulator in human diseases
Accumulation and turnover of extracellular matrix components are the hallmarks of tissue
injury. Fragmented hyaluronan stimulates the expression of inflammatory genes by a variety …
injury. Fragmented hyaluronan stimulates the expression of inflammatory genes by a variety …