Probiotics are currently the subject of intensive research pursuits and also represent a multi-
billion-dollar global industry given their vast potential to improve human health. In addition …

The Parkinson's Progression Markers Initiative (PPMI) has collected more than a decade's
worth of longitudinal and multi-modal data from patients, healthy controls, and at-risk …

Precision medicine for Alzheimer's disease (AD) necessitates the development of
personalized, reproducible, and neuroscientifically interpretable biomarkers, yet despite …

This systematic review synthesizes evidence from research investigating the biological
correlates of latent transdiagnostic dimensions of psychopathology (eg, the p-factor …

Highlights•Computational psychiatry holds promise for mechanistic discovery in
addiction.•This approach captures latent factors driving behavioral differences from …

Assessment of mental illness typically relies on a disorder classification system that is
considered to be at odds with the vast disorder comorbidity and symptom heterogeneity that …

Neurodegenerative disorders exhibit considerable clinical heterogeneity and are frequently
misdiagnosed. This heterogeneity is often neglected and difficult to study. Therefore …

Resting-state functional connectivity (RSFC) is a powerful tool for characterizing brain
changes, but it has yet to reliably predict higher-order cognition. This may be attributed to …

Background Autism spectrum disorder (ASD) is a complex neurodevelopmental disorder
characterized by substantial clinical and biological heterogeneity. Quantitative and …

Autism is a heterogeneous neurodevelopmental condition, and functional magnetic
resonance imaging–based studies have helped advance our understanding of its effects on …