Major depressive disorder (MDD) is a psychiatric disease of still poorly understood
molecular etiology. Extensive studies at different molecular levels point to a high complexity …

Highlights•The Reactive Oxygen Species have an utmost importance in progression of
Depression.•Depression is associated with lowered concentration of anti-oxidants in …

Major depressive disorder (MDD) is a common, debilitating, phenotypically heterogeneous
disorder with heritability ranges from 30% to 50%. Compared to other psychiatric disorders …

Background Few studies have investigated the relationship between systemic oxidative
stress status and depression. The oxidative balance score (OBS) was used to assess …

Treatment of neurodegenerative diseases or other central nervous system (CNS) disorders
has always been a significant challenge. The nature of the blood-brain barrier (BBB) limits …

Cytokines have been implicated in the pathology of depression. Currently, the evidence is
based on cross-sectional studies and meta-analytic research comparing blood …

There is a large evidence base supporting an important role of parenting behavior in
influencing youth mental health; however, this literature often fails to capture the potentially …

Depression is a mental health disorder that develops as a result of complex psycho-neuro-
immuno-endocrinological disturbances. This disease presents with mood disturbances …

Mental disorders represent critical public health challenges as they are leading contributors
to the global burden of disease and intensely influence social and financial welfare of …

Major depressive disorder (MDD) is a heterogeneous disease affecting one out of five
individuals and is the leading cause of disability worldwide. Presently, MDD is considered a …