Background. The unique pharmacological properties of buprenorphine may make it a useful
maintenance therapy for opiate addiction. This meta‐analysis considers the effectiveness of …

Opioids are very effective analgesics, but they are also highly addictive. Methadone is used
to treat opioid dependence (OD), acting as a selective agonist at the μ-opioid receptor …

Objective: The objective of this secondary analysis was to explore differences in baseline
clinical characteristics and opioid replacement therapy treatment outcomes by type (heroin …

Background Switzerland has been criticised for its liberal drug policy, which could attract
new users and lengthen periods of heroin addiction. We sought to estimate incidence trends …

The present study compared in a clinical non-experimental setting the efficacy of
buprenorphine (BUP) and methadone (METH) in the treatment of opioid dependence: all the …

This study sought to determine whether select pretreatment demographic and in-treatment
clinical variables predict premature treatment discharge at 6 and 12 months among patients …

Background Polydrug abuse is a known problem among opioid-dependent patients
receiving opioid maintenance treatment (OMT). However, improved laboratory diagnostics is …

Background Although methadone maintenance is an effective therapy for heroin
dependence, some patients continue to use heroin and may benefit from therapeutic …

The aims were to identify predictors of treatment retention in an Israeli methadone
maintenance treatment (MMT) clinic, and to compare the findings to other international …

In 1989, the National Institute on Drug Abuse (NIDA) established its Medications
Development Program. This program has concentrated on developing pharmacotherapies …