[HTML][HTML] Inhaled cannabis for chronic neuropathic pain: a meta-analysis of individual patient data
MH Andreae, GM Carter, N Shaparin, K Suslov… - The Journal of …, 2015 - Elsevier
Chronic neuropathic pain, the most frequent condition affecting the peripheral nervous
system, remains underdiagnosed and difficult to treat. Inhaled cannabis may alleviate …
system, remains underdiagnosed and difficult to treat. Inhaled cannabis may alleviate …
[HTML][HTML] Combination drug therapy for chronic pain: a call for more clinical studies
J Mao, MS Gold - The Journal of Pain, 2011 - Elsevier
Chronic pain is a debilitating clinical condition associated with a variety of disease entities
including diabetic neuropathy, postherpetic neuralgia, low back pathology, fibromyalgia, and …
including diabetic neuropathy, postherpetic neuralgia, low back pathology, fibromyalgia, and …
NGX-4010, a high-concentration capsaicin patch, for the treatment of postherpetic neuralgia: a randomised, double-blind study
M Backonja, MS Wallace, ER Blonsky… - The Lancet …, 2008 - thelancet.com
Background The limitations of current treatments for postherpetic neuralgia (PHN) have led
to the investigation of localised, non-systemic alternatives. NGX-4010, a high-concentration …
to the investigation of localised, non-systemic alternatives. NGX-4010, a high-concentration …
Genetic disruption of both tryptophan hydroxylase genes dramatically reduces serotonin and affects behavior in models sensitive to antidepressants
KV Savelieva, S Zhao, VM Pogorelov, I Rajan, Q Yang… - PloS one, 2008 - journals.plos.org
The neurotransmitter serotonin (5-HT) plays an important role in both the peripheral and
central nervous systems. The biosynthesis of serotonin is regulated by two rate-limiting …
central nervous systems. The biosynthesis of serotonin is regulated by two rate-limiting …
[HTML][HTML] Comparison of oxaliplatin-and cisplatin-induced painful peripheral neuropathy in the rat
EK Joseph, JD Levine - The Journal of Pain, 2009 - Elsevier
Although platinum-based cancer chemotherapies produce painful peripheral neuropathy as
dose-limiting side effects, there are important differences in the pain syndromes produced by …
dose-limiting side effects, there are important differences in the pain syndromes produced by …
Effectiveness of the capsaicin 8% patch in the management of peripheral neuropathic pain in European clinical practice: the ASCEND study
C Mankowski, CD Poole, E Ernault, R Thomas, E Berni… - BMC neurology, 2017 - Springer
Background In randomised studies, the capsaicin 8% patch has demonstrated effective pain
relief in patients with peripheral neuropathic pain (PNP) arising from different aetiologies …
relief in patients with peripheral neuropathic pain (PNP) arising from different aetiologies …
Intrathecal ziconotide for neuropathic pain: a review
RL Rauck, MS Wallace, AW Burton, L Kapural… - Pain …, 2009 - Wiley Online Library
Neuropathic pain is a considerable burden that affects activities of daily living. The
management of neuropathic pain can be challenging because of multiple etiologies and …
management of neuropathic pain can be challenging because of multiple etiologies and …
Sodium channels and nociception: recent concepts and therapeutic opportunities
DS Krafte, AW Bannon - Current opinion in pharmacology, 2008 - Elsevier
Recent scientific advances have enhanced our understanding of the role voltage-gated
sodium channels play in pain sensation. Human data on Nav1. 7 show that gain-of-function …
sodium channels play in pain sensation. Human data on Nav1. 7 show that gain-of-function …
Neuronal loss in the rostral ventromedial medulla in a rat model of neuropathic pain
ML Leong, M Gu, R Speltz-Paiz, EI Stahura… - Journal of …, 2011 - Soc Neuroscience
Cell death has been reported in the CNS in models of neuropathic pain (;;;). In our present
study, we examined the effects of spinal nerve ligation (SNL) on the number of neurons in …
study, we examined the effects of spinal nerve ligation (SNL) on the number of neurons in …
Ziconotide monotherapy: a systematic review of randomised controlled trials
ME Brookes, S Eldabe… - Current …, 2017 - ingentaconnect.com
Introduction: Chronic neuropathic pain is difficult to treat and is often refractory to most
modalities of treatment. Ziconotide is a novel, potent, non-opioid, calcium channel blocking …
modalities of treatment. Ziconotide is a novel, potent, non-opioid, calcium channel blocking …