Toward merging untargeted and targeted methods in mass spectrometry-based metabolomics and lipidomics
Advances in mass spectrometry (MS) and data processing have led to discoveries in
regulation of cellular metabolism by using metabolomics and lipidomics approaches. 1, 2 …
regulation of cellular metabolism by using metabolomics and lipidomics approaches. 1, 2 …
Metabolomics: a primer
X Liu, JW Locasale - Trends in biochemical sciences, 2017 - cell.com
Metabolomics generates a profile of small molecules that are derived from cellular
metabolism and can directly reflect the outcome of complex networks of biochemical …
metabolism and can directly reflect the outcome of complex networks of biochemical …
Quality assurance procedures for mass spectrometry untargeted metabolomics. a review
Untargeted metabolomics, as a global approach, has already proven its great potential and
capabilities for the investigation of health and disease, as well as the wide applicability for …
capabilities for the investigation of health and disease, as well as the wide applicability for …
Recent advances in LC‐MS‐based metabolomics for clinical biomarker discovery
The employment of liquid chromatography‐mass spectrometry (LC‐MS) untargeted and
targeted metabolomics has led to the discovery of novel biomarkers and improved the …
targeted metabolomics has led to the discovery of novel biomarkers and improved the …
Metabolomics: the apogee of the omics trilogy
Metabolites, the chemical entities that are transformed during metabolism, provide a
functional readout of cellular biochemistry. With emerging technologies in mass …
functional readout of cellular biochemistry. With emerging technologies in mass …
Nutrimetabolomics: an integrative action for metabolomic analyses in human nutritional studies
MM Ulaszewska, CH Weinert… - Molecular nutrition & …, 2019 - Wiley Online Library
The life sciences are currently being transformed by an unprecedented wave of
developments in molecular analysis, which include important advances in instrumental …
developments in molecular analysis, which include important advances in instrumental …
Procedures for large-scale metabolic profiling of serum and plasma using gas chromatography and liquid chromatography coupled to mass spectrometry
WB Dunn, D Broadhurst, P Begley, E Zelena… - Nature protocols, 2011 - nature.com
Metabolism has an essential role in biological systems. Identification and quantitation of the
compounds in the metabolome is defined as metabolic profiling, and it is applied to define …
compounds in the metabolome is defined as metabolic profiling, and it is applied to define …
The growing role of precision and personalized medicine for cancer treatment
Cancer is a devastating disease that takes the lives of hundreds of thousands of people
every year. Due to disease heterogeneity, standard treatments, such as chemotherapy or …
every year. Due to disease heterogeneity, standard treatments, such as chemotherapy or …
Metabolomics analysis reveals large effects of gut microflora on mammalian blood metabolites
Although it has long been recognized that the enteric community of bacteria that inhabit the
human distal intestinal track broadly impacts human health, the biochemical details that …
human distal intestinal track broadly impacts human health, the biochemical details that …
Global metabolic profiling procedures for urine using UPLC–MS
The production of'global'metabolite profiles involves measuring low molecular-weight
metabolites (< 1 kDa) in complex biofluids/tissues to study perturbations in response to …
metabolites (< 1 kDa) in complex biofluids/tissues to study perturbations in response to …