Lung densitometry assesses with computed tomography (CT) the X-ray attenuation of the
pulmonary tissue which reflects both the degree of inflation and the structural lung …

Current epidemiologic practice evaluates COPD based on self-reported symptoms of
chronic bronchitis, self-reported physician-diagnosed COPD, spirometry confirmed airflow …

Rationale: Computed tomography (CT)-based lung density is used to quantitate the
percentage of emphysema-like lung (hereafter referred to as percent emphysema), but …

Rationale: The Global Lung Initiative (GLI) provides age-appropriate criteria for establishing
spirometric impairment, including mild, moderate, and severe chronic obstructive pulmonary …

Rationale: In aging populations, the commonly used Global Initiative for Chronic Obstructive
Lung Disease (GOLD) may misclassify normal spirometry as respiratory impairment (airflow …

Rationale: Quantitative computed tomography (CT) has been used to phenotype patients
with chronic obstructive pulmonary disease (COPD). A mixed phenotype is defined as the …

Computed tomography (CT) has contributed substantially to our understanding of COPD
over the past decade. Visual and quantitative assessments of CT in COPD are …

Objective To longitudinally evaluate effects of smoking cessation on quantitative CT in a
lung cancer screening cohort of heavy smokers over 4 years. Methods After 4 years, low …

Objectives Quantitative multidetector computed tomography (MDCT) as a potential
biomarker is increasingly used for severity assessment of emphysema in chronic obstructive …

Rationale: The definition of primary spontaneous pneumothorax excludes patients with
known lung disease; however, the assumption that the underlying lung is normal in these …