Boron-containing compounds for prevention, diagnosis, and treatment of human metabolic disorders

CC Ri, CR Mf, S IR, SU MA - Biological trace element research, 2023 - Springer
The application of natural and synthetic boron-containing compounds (BCC) in biomedical
field is expanding. BCC have effects in the metabolism of living organisms. Some boron …

Boron compounds exhibit protective effects against aluminum-induced neurotoxicity and genotoxicity: In vitro and in vivo study

H Turkez, S Yıldırım, E Sahin, ME Arslan, B Emsen… - Toxics, 2022 - mdpi.com
Genetic, neuropathological and biochemical investigations have revealed meaningful
relationships between aluminum (Al) exposure and neurotoxic and hematotoxic damage …

Antibacterial activity of boron compounds against biofilm-forming pathogens

O Celebi, D Celebi, S Baser, E Aydın, E Rakıcı… - … Trace Element Research, 2024 - Springer
This study aimed to evaluate the antibacterial activity of nine boron derivatives against
biofilm-forming pathogenic bacteria. The effect of boron derivatives (CMB, calcium …

Interrupted Homolytic Substitution Enables Organoboron Compounds to Inhibit Radical Chain Reactions Rather than Initiate Them

Z Wu, R Vlaming, M Donohoe… - Journal of the American …, 2023 - ACS Publications
The reactions of organoboranes with peroxyl radicals are key to their use as radical initiators
for a vast array of radical chain reactions, particularly at low temperatures where high …

Boron derivatives inhibit the proliferation of breast cancer cells and affect tumor-specific T cell activity in vitro by distinct mechanisms

EE Mohammed, N Türkel, UM Yigit, AB Dalan… - … Trace Element Research, 2023 - Springer
Breast cancer is the most frequently diagnosed cancer among women worldwide. Despite
the initial clinical response obtained with the widely used conventional chemotherapy, an …

Boron-assisted abiotic polypeptide synthesis

Y Sumie, K Sato, T Kakegawa… - Communications Chemistry, 2023 - nature.com
The emergence of proteins and their interactions with RNAs were a key step in the origin
and early evolution of life. The abiotic synthesis of peptides has been limited in short amino …

Effect of coating with chitosan enriched with different borates on the shelf life of fish fillet

G Alak, A Ucar, V Parlak, H Turkez… - Journal of the …, 2023 - Wiley Online Library
BACKGROUND In this study, the effects of biofilm coatings obtained by immobilization of
different borates–namely borax (BX), colemanite (COL), and ulexite (UX)–with chitosan (Ch) …

Boron Compound–Based Treatments Against Multidrug-Resistant Bacterial Infections in Lung Cancer In Vitro Model

D Celebı, O Celebı, E Aydin, S Baser, MC Güler… - … Trace Element Research, 2024 - Springer
Multidrug-resistant bacteria is one of the most important public health problems. Increasing
rates of antibacterial resistance also affect the outcomes of medical approaches. Cancer …

BGM, a Newly Synthesised Boron Compound, Induces Apoptosis and Reduces Oxidative Stress by Inhibiting Lipogenesis in 3T3-L1 Adipocytes via PPARγ and …

M Koldemir Gündüz - Biological Trace Element Research, 2022 - Springer
Obesity is a chronic disease associated with increased morbidity and mortality. The rapidly
increasing prevalence of obesity makes it a global health problem, while treatment options …

Study of novel bidentate heterocyclic amine-based metal complexes and their biological activities: cytotoxicity and antimicrobial activity evaluation

HM Fahmy, FM Abdel-Rahman, AA El-Sayed… - BMC chemistry, 2023 - Springer
Metallic antitumor drugs with heterocyclic ligands, such as novel AMI (amino methyl
imidazole) complexes [Pd (AMI) Cl2](1),[Cu (AMI) L1](2), and [Cu (AMI) L2· 2H2O](3) where …