Various interferon (IFN)-stimulated genes (ISGs), expressed via Janus kinase–signal
transducer and activator of transcription (JAK-STAT) signaling pathway-stimulated IFNs to …

A defining feature of a productive viral infection is the co-opting of host cell resources for
viral replication. Despite the host repertoire of molecular functions and biological counter …

Abstract Enterovirus A71 (EV‐A71) is a highly contagious virus that poses a major threat to
global health, representing the primary etiological agent for hand–foot and mouth disease …

Mice are refractory to infection with human-tropic hepatitis C virus (HCV), although distantly
related rodent hepaciviruses (RHV) circulate in wild rodents. To investigate whether liver …

Type I interferons (IFN-Is) are pivotal in innate immunity against human immunodeficiency
virus I (HIV-1) by eliciting the expression of IFN-stimulated genes (ISGs), which encompass …

The innate immune system, particularly the interferon (IFN) system, constitutes the initial line
of defense against viral infections. IFN signaling induces the expression of interferon …

P-bodies (PB) are non-membranous foci involved in determining mRNA fate by affecting
translation and mRNA decay. In this study, we identify the anti-viral factor SHFL as a potent …

A defining feature of a productive infection is the co-opting of host cell resources for viral
replication. Despite their repertoire of molecular functions, viruses subvert host defenses to …

Viruses often pose a significant threat to the host through the exploitation of cellular
machineries for their own benefit. In the context of immune responses, myriad host factors …

Herpesviruses are evolutionarily robust parasites. Following entry into the host, their
biphasic lifecycle promotes a lifelong infection and a nearly global distribution of virus …