AIMS: Adenosine administration is needed for the achievement of maximal hyperaemia
fractional flow reserve (FFR) assessment. The objective was to test the accuracy of Pd/Pa …

Abstract Background Adenosine-free indexes (AFIs), including resting Pd/Pa, instantaneous
wave-free ratio (iFR) and contrast-FFR (cFFR), have been proposed to circumvent the use of …

Background—Contrast fractional flow reserve (cFFR) is a method for assessing functional
significance of coronary stenoses, which is more accurate than resting indices and does not …

Aim To review the current approaches to simplify functional assessment of coronary stenosis
with particular regard for contrast Fractional Flow Reserve (cFFR). Methods and results …

Objective: It remains controversial whether patients with fractional flow reserve (FFR) values
of 0.75–0.80 (gray-zone) should be treated with percutaneous coronary intervention (PCI) …

Objective Measuring the fractional flow reserve (FFR) requires the induction of coronary
hyperemia, usually with adenosine, adenosine triphosphate (ATP), or papaverine. However …

Objective: For fractional flow reserve measurement, contrast media can be used as an
alternative for adenosine. However, contrast media with different physical characteristics …

Angiography is inaccurate in assessing functional significance of coronary lesions, and often
stenoses deemed severe on angiographic assessment do not restrict coronary blood flow at …

Results: After bolus ic adenosine, 12 lesions of 34 (35.3%) were identified as significant. The
CMR value was 0.86±0.06 (range: 0.71–0.97). There were no significant differences …

Physiologic assessment using fractional flow reserve (FFR) to guide percutaneous coronary
interventions (PCI) has been demonstrated to improve clinical outcomes, compared to …