Molecular genetics and general management of androgen insensitivity syndrome

Z Chen, P Li, Y Lyu, Y Wang, K Gao, J Wang… - Intractable & Rare …, 2023 - jstage.jst.go.jp
Androgen insensitivity syndrome (AIS) is a rare genetic disorder that affects the development
of the male reproductive system in individuals with a 46, XY karyotype. In addition to …

Urogenital sinus malformation: From development to management

Y Ding, Y Wang, Y Lyu, H Xie, Y Huang… - Intractable & Rare …, 2023 - jstage.jst.go.jp
Urogenital sinus (UGS) malformation, also known as persistent urogenital sinus (PUGS), is a
rare congenital malformation of the urogenital system. It arises when the urethra and vaginal …

The association and underlying mechanism of the digit ratio (2D: 4D) in hypospadias

Y Ding, ZQ Chen, WF Pan, HJ Chen, M Wu… - Asian Journal of …, 2024 - journals.lww.com
The second-to-fourth digit (2D: 4D) ratio is thought to be associated with prenatal androgen
exposure. However, the relationship between the 2D: 4D ratio and hypospadias is poorly …

MicroR-1199-5p targeting SRD5A2 promotes the biological behavior and EMT of hypospadias cells

Y Chen, J Hu, L Peng, Y Zhao - Cellular and Molecular Biology, 2024 - cellmolbiol.org
Hypospadias, an oft-occurring penis anomaly, ranks among neonatal's foremost birth
defects. The SRD5A2 can affect male reproductive system development and is abnormally …

Etiology of Hypospadias: a Systematic Review of Genetic Variants.

FU Yuan, LI Jian-Ting… - Chinese Journal of …, 2024 - search.ebscohost.com
Hypospadias, characterized by abnormal position of the urethral opening, is the second
most common congenital anomaly in men. Its incidence is increasing year by year, and it …

Motor proteins, spermatogenesis and testis function

L Wang, T Bu, X Wu, L Li, F Sun… - Advances in protein …, 2024 - pubmed.ncbi.nlm.nih.gov
The role of motor proteins in supporting intracellular transports of vesicles and organelles in
mammalian cells has been known for decades. On the other hand, the function of motor …