Neuroprotective effects of lactoferrin in Alzheimer's and Parkinson's diseases: A narrative review
Recent advancements in lactoferrin research have uncovered that lactoferrin does function
not only as an antimicrobial protein but also as an immunomodulatory, anticancer, and …
not only as an antimicrobial protein but also as an immunomodulatory, anticancer, and …
Viral involvement in Alzheimer's disease
Alzheimer's disease (AD) is characterized by the presence of β-amyloid plaques (Aβ) and
neurofibrillary tangles (NFTs) in the brain. The prevalence of the disease is increasing and is …
neurofibrillary tangles (NFTs) in the brain. The prevalence of the disease is increasing and is …
The Cryo-EM structures of two amphibian antimicrobial cross-β amyloid fibrils
The amyloid-antimicrobial link hypothesis is based on antimicrobial properties found in
human amyloids involved in neurodegenerative and systemic diseases, along with …
human amyloids involved in neurodegenerative and systemic diseases, along with …
Depletion of NK cells improves cognitive function in the Alzheimer disease mouse model
Y Zhang, ITH Fung, P Sankar, X Chen… - The Journal of …, 2020 - journals.aai.org
Despite mounting evidence suggesting the involvement of the immune system in regulating
brain function, the specific role of immune and inflammatory cells in neurodegenerative …
brain function, the specific role of immune and inflammatory cells in neurodegenerative …
HHV-6A infection induces amyloid-beta expression and activation of microglial cells
Background The control of viral infections in the brain involves the activation of microglial
cells, the macrophages of the brain that are constantly surveying the central nervous system …
cells, the macrophages of the brain that are constantly surveying the central nervous system …
The role of antimicrobial peptides in influenza virus infection and their potential as antiviral and immunomodulatory therapy
IN Hsieh, KL Hartshorn - Pharmaceuticals, 2016 - mdpi.com
Influenza A virus (IAV) remains a major threat that can cause severe morbidity and mortality
due to rapid genomic variation. Resistance of IAVs to current anti-IAV drugs has been …
due to rapid genomic variation. Resistance of IAVs to current anti-IAV drugs has been …
Controversial properties of amyloidogenic proteins and peptides: new data in the COVID era
A Surguchov, FN Emamzadeh, M Titova, AA Surguchev - Biomedicines, 2023 - mdpi.com
For a long time, studies of amyloidogenic proteins and peptides (amyloidogenic PPs) have
been focused basically on their harmful properties and association with diseases. A vast …
been focused basically on their harmful properties and association with diseases. A vast …
Indication of neurodegenerative cascade initiation by amyloid-like aggregate-forming EBV proteins and peptide in Alzheimer's disease
The neurotropic potential of the Epstein-Barr virus (EBV) was demonstrated quite recently;
however, the mechanistic details are yet to be explored. Therefore, the effects of EBV …
however, the mechanistic details are yet to be explored. Therefore, the effects of EBV …
The increased amyloidogenicity of spike RBD and pH-dependent binding to ACE2 may contribute to the transmissibility and pathogenic properties of SARS-CoV-2 …
AY Aksenova, IV Likhachev, SY Grishin… - International Journal of …, 2022 - mdpi.com
SARS-CoV-2 is a rapidly evolving pathogen that has caused a global pandemic
characterized by several consecutive waves. Based on epidemiological and NGS data …
characterized by several consecutive waves. Based on epidemiological and NGS data …
Insights into the potential role of mercury in Alzheimer's disease
Mercury (Hg), which is a non-essential element, is considered a highly toxic pollutant for
biological systems even when present at trace levels. Elevated Hg exposure with the …
biological systems even when present at trace levels. Elevated Hg exposure with the …