Large-scale genome-wide association studies have consistently shown that genetic
variation in CACNA1C, a gene that encodes calcium voltage-gated channel subunit …

The L-type calcium channels (LTCCs) Ca v 1.2 and Ca v 1.3, encoded by the CACNA1C
and CACNA1D genes, respectively, are important regulators of calcium influx into cells and …

The importance of neuronal ensembles, termed engram cells, in storing and retrieving
memory is increasingly being appreciated, but less is known about how these engram cells …

This review describes interactions between compounds, primarily dihydropyridines, that
block L-type calcium channels and drugs that cause dependence, and the potential …

Voltage-gated calcium channels (VGCCs) are widely expressed in the brain, heart and
vessels, smooth and skeletal muscle, as well as in endocrine cells. VGCCs mediate gene …

Abstract Brain Cav1. 2 and Cav1. 3 L‐type Ca2+ channels play key physiological roles in
various neuronal processes that contribute to brain function. Genetic studies have recently …

We reappraise the psychiatric potential of calcium channel blockers (CCBs). First, voltage-
gated calcium channels are risk genes for several disorders. Second, use of CCBs is …

Genetic factors significantly influence susceptibility for substance abuse and mood
disorders. Rodent studies have begun to elucidate a role of Ca v 1.3 L-type Ca 2+ channels …

Voltage‐gated L‐type Ca2+‐channels (LTCCs) are the target of Ca2+‐channel blockers
(CCBs), which are in clinical use for the evidence‐based treatment of hypertension and …

Background Neuropsychiatric disorders are highly heritable and have overlapping genetic
underpinnings. Single nucleotide polymorphisms (SNPs) in the gene CACNA1C have been …