Background. Malignant tumor is one of the most common diseases that seriously affect
human health. The prior literature has reported the biological function and potential …

Objective Aberrant epigenetic remodeling represents a molecular hallmark in lung
adenocarcinoma (LUAD). We aim to investigate the biological roles of SETDB2 and its …

Transfer RNA (tRNA)-derived small RNAs (tsRNAs) are a new type of non-coding RNAs
(ncRNAs) produced by the specific cleavage of precursor or mature tRNAs. tsRNAs are …

Simple Summary The global methylation profile of two human metastatic colorectal
carcinoma subgroups with significantly different outcomes (primary-resistant versus drug …

The tumor microenvironment (TME) is crucial to neoplastic processes, fostering proliferation,
angiogenesis and metastasis. Epigenetic regulations, primarily including DNA and RNA …

Simple Summary Epigenetic changes in a cell's genome can cause the inactivation of genes
and affect how tumours respond to chemotherapy. These epigenetic changes do not alter …

Diabetic kidney disease (DKD) is a common microangiopathy in diabetic patients and the
main cause of death in diabetic patients. The main manifestations of DKD are proteinuria …

The naturally occurring phenomenon of bioluminescence has intrigued on-lookers for
decades and is now being developed as a powerful tool for medical research and preclinical …

Since the breakthrough discovery of N6-methyladenosine (m 6 A), the field of RNA
epitranscriptomics has attracted increasing interest in the biological sciences. Transfer …

Pulmonary lymphoepithelioma‐like carcinoma (pLELC) is a rare malignancy that lacks
specific biomarkers. N6‐methyladenosine (m6A) is the most widespread internal …