Sarcopenia is an age-associated loss of skeletal muscle mass, strength, and function,
accompanied by severe adverse health outcomes, such as falls and fractures, functional …

Microbial synthetic epigenetics offers significant opportunities for the design of synthetic
biology tools by leveraging reversible gene control mechanisms without altering DNA …

Simple Summary Medulloblastoma is the most common malignant pediatric brain tumor and
is classified into four molecular subgroups: Wnt, Shh, Group 3, and Group 4. Of these …

In recent years, developing the idea of “cancer big data” has emerged as a result of the
significant expansion of various fields such as clinical research, genomics, proteomics and …

Epigenetics is the study of heritable changes in gene expression or function without altering
the DNA sequence. Important factors are part of epigenetic events, such as methylation …

Breast cancer represents a health concern worldwide for being the leading cause of cancer-
related women's death. The main challenge for breast cancer treatment involves its …

Pharmacogenetics, the study of how interindividual genetic differences affect drug response,
does not explain all observed heritable variance in drug response. Epigenetic mechanisms …

Alterations in the epigenetic machinery in both tumor and immune cells contribute to bladder
cancer (BC) development, constituting a promising target as an alternative therapeutic …

Background The Chromobox homolog 4 (CBX4) has been found to be overexpressed in
multiple malignancies. However, the associations between CBX4 and gastric cancer (GC) …

Background Colorectal cancer is the most common malignancy and the third leading cause
of cancer-related death worldwide. This study aimed to identify potential diagnostic …