It has been reported that an increased population of regulatory T cells (Tregs) is one of the
reasons for impaired anti‐tumor immunity. Recently, Foxp3 has been reported as a reliable …

It is now widely accepted that the normal immune system harbors a regulatory T‐cell
population specialized for immune suppression. It was found initially that some CD4+ T cells …

Abstract Objective To investigate whether Treg cells can suppress osteoclast differentiation,
and to define a new potential link between the immune system and the skeleton. Methods …

Rheumatoid arthritis (RA) is one of the most common chronic inflammatory syndromes. As
such, RA is often considered the prototype disease for defining both the molecular and …

Regulatory T cells (Tregs) suppress exuberant immune system activation and promote
immunologic tolerance. Because Tregs modulate both innate and adaptive immunity, the …

Purpose Sepsis syndrome represents the leading cause of death in intensive care unit.
Patients present features consistent with a decline in immune responsiveness potentially …

Multiple myeloma (MM) is typically exemplified by a desynchronized cytokine system with
increased levels of inflammatory cytokines. We focused on the contrast between …

The SARS-CoV-2 virus has caused a worldwide COVID-19 pandemic. In less than a year
and a half, more than 200 million people have been infected and more than four million …

Purpose: T-cell infiltration is associated with good tumor prognosis in many cancers. To
assess the capacity of neoadjuvant chemotherapy to affect T-cell infiltration in breast cancer …

Summary CD4+ Foxp3+ regulatory T (Treg) cells originate primarily from thymic
differentiation, but conversion of mature T lymphocytes to Foxp3 positivity can be elicited by …