Neutrophils Protect Against Staphylococcus aureus Endocarditis Progression Independent of Extracellular Trap Release
S Meyers, M Lox, S Kraisin… - … and Vascular Biology, 2023 - Am Heart Assoc
Background: Infective endocarditis (IE) is characterized by an infected thrombus at the heart
valves. How bacteria bypass the immune system and cause these thrombi remains unclear …
valves. How bacteria bypass the immune system and cause these thrombi remains unclear …
Impact of Vancomycin on sarA-Mediated Biofilm Formation: Role in Persistent Endovascular Infections Due to Methicillin-Resistant Staphylococcus aureus
W Abdelhady, AS Bayer, K Seidl… - The Journal of …, 2014 - academic.oup.com
Background. Staphylococcus aureus is the most common cause of endovascular infections.
The staphylococcal accessory regulator A locus (sarA) is a major virulence determinant that …
The staphylococcal accessory regulator A locus (sarA) is a major virulence determinant that …
Clinical S. aureus Isolates Vary in Their Virulence to Promote Adaptation to the Host
L Tuchscherr, C Pöllath, A Siegmund… - Toxins, 2019 - mdpi.com
Staphylococcus aureus colonizes epithelial surfaces, but it can also cause severe infections.
The aim of this work was to investigate whether bacterial virulence correlates with defined …
The aim of this work was to investigate whether bacterial virulence correlates with defined …
Phenotypic and Genotypic Characteristics of Methicillin-Resistant Staphylococcus aureus (MRSA) Related to Persistent Endovascular Infection
Persistent methicillin-resistant Staphylococcus aureus (MRSA) bacteremia (PB) represents
an important subset of S. aureus infection and correlates with poor clinical outcomes. MRSA …
an important subset of S. aureus infection and correlates with poor clinical outcomes. MRSA …
All Staphylococcus aureus bacteraemia-inducing strains can cause infective endocarditis: Results of GWAS and experimental animal studies
S Bastien, S Meyers, W Salgado-Pabón, SG Giulieri… - Journal of Infection, 2023 - Elsevier
Objectives We aimed at determining whether specific S. aureus strains cause infective
endocarditis (IE) in the course of Staphylococcus aureus bacteraemia (SAB). Methods A …
endocarditis (IE) in the course of Staphylococcus aureus bacteraemia (SAB). Methods A …
Role of Purine Biosynthesis in Persistent Methicillin-Resistant Staphylococcus aureus Infection
Persistent methicillin-resistant Staphylococcus aureus (MRSA) bacteremia (PB) represents
an important subset of S. aureus endovascular infections. In this study, we investigated …
an important subset of S. aureus endovascular infections. In this study, we investigated …
Reduced Vancomycin Susceptibility in an In Vitro Catheter-Related Biofilm Model Correlates with Poor Therapeutic Outcomes in Experimental Endocarditis Due to …
W Abdelhady, AS Bayer, K Seidl, CC Nast… - Antimicrobial agents …, 2013 - Am Soc Microbiol
Staphylococcus aureus is the most common cause of endovascular infections, including
catheter sepsis and infective endocarditis (IE). Vancomycin (VAN) is the primary choice for …
catheter sepsis and infective endocarditis (IE). Vancomycin (VAN) is the primary choice for …
The MTT assay is a rapid and reliable quantitative method to assess Staphylococcus aureus induced endothelial cell damage
K Seidl, AS Zinkernagel - Journal of microbiological methods, 2013 - Elsevier
We established the 3-(4, 5-Dimethylthiazol-2-yl)-2, 5-diphenyltetrazolium bromide (MTT)
assay to assess damage induced by Staphylococcus aureus in human umbilical vein …
assay to assess damage induced by Staphylococcus aureus in human umbilical vein …
The Stringent Response Contributes to Persistent Methicillin-Resistant Staphylococcus aureus Endovascular Infection Through the Purine Biosynthetic Pathway
L Li, AS Bayer, A Cheung, L Lu… - The Journal of …, 2020 - academic.oup.com
Persistent methicillin-resistant Staphylococcus aureus (MRSA) endovascular infections
represent a significant clinical-therapeutic challenge. Of particular concern is antibiotic …
represent a significant clinical-therapeutic challenge. Of particular concern is antibiotic …
Subinhibitory concentrations of antibiotics exacerbate staphylococcal infection by inducing bacterial virulence
P Gao, Y Wei, RE Wan, KW Wong, HTV Iu… - Microbiology …, 2022 - Am Soc Microbiol
Antibiotics are widely used for the treatment of bacterial infections. However, injudicious use
of antibiotics based on an empirical method may lead to the emergence of resistant strains …
of antibiotics based on an empirical method may lead to the emergence of resistant strains …