Microtubules (MTs), highly dynamic structures composed of α-and β-tubulin heterodimers,
are involved in cell movement and intracellular traffic and are essential for cell division …

Abstract Knowledge of the molecular mechanisms on malignant tumors is very critical for the
development of new treatment strategies like molecularly targeted therapies. In last 5 years …

Background We examined a large cohort of serous tubo-ovarian tumors with 26
immunohistochemical markers, with the aim to assess their value for differential diagnosis …

Abstract Background Upregulation of Stathmin 1 (STMN1), a cytoplasmic phosphoprotein
that controls the dynamics of cellular microtubules, is linked to malignant behavior and poor …

Esophageal cancer (EC) is one of the most incident and lethal tumors worldwide. Although
surgical resection is an important approach in EC treatment, late diagnosis, metastasis and …

Bladder cancer (BCa) is an aggressive malignancy because of its distant metastasis and
high recurrence rate. Circular RNAs (circRNAs) exert critical regulatory functions in cancer …

Long treatment with paclitaxel (PTX) might increase resistance and side-effects causing a
failure in cancer chemotherapy. Here we uncovered that either sulforaphane-cysteine (SFN …

Cetuximab (CTX) is known to have cytotoxic effects on several human cancer cells in vitro;
however, as CTX is poorly water soluble, there is a need for improved formulations can …

Background: Hierridin B was isolated from a marine cyanobacterium Cyanobium sp. strain
and induced cytotoxicity selectively in HT-29 adenocarcinoma cells. The underlying …

Background Modern fast-growing broilers are susceptible to heart failure under heat stress
because their relatively small hearts cannot meet increased need of blood pumping. To …