Kidney diseases remain one of the leading causes of human death and have placed a
heavy burden on the medical system. Regulated cell death contributes to the pathology of a …

Uridine metabolism is extensively reported to be involved in combating oxidative stress.
Redox-imbalance-mediated ferroptosis plays a pivotal role in sepsis-induced acute lung …

Currently, cancer remains one of the most significant threats to human health. Treatment of
most cancers remains challenging, despite the implementation of diverse therapies in …

Ferroptosis is a form of programmed cell death mostly characterized by a serious
misadjustment in the production and degradation of lipid reactive oxygen species (ROS) …

Background Ferroptosis plays an important role in acute kidney injury (AKI), but the specific
regulatory mechanism of ferroptosis in AKI remains unclear. This study is expected to …

Inflammation is a biological response of multicellular organisms caused by injuries,
pathogens or irritants. An excessive inflammatory response can lead to tissue damage and …

Ferroptosis is a non-apoptotic form of cell death characterized by iron-dependent lipid
peroxidation and glutathione (GSH) depletion. Despite recent advances, challenges remain …

Ferroptosis, an iron-dependent regulated cell death, has been emerging as an early
mechanism in anticancer drug-induced acute kidney injury (AKI) that may benefit therapeutic …

Abstracts Contrast-induced acute kidney injury (CI-AKI) is a prevalent cause of renal
dysfunction among hospitalized patients, yet the precise pathogenesis and effective …

Background: Penehyclidine hydrochloride (PHC) has been shown to be effective in the
treatment of rhabdomyolysis (RM)-induced acute kidney injury (AKI). Our research sought to …