Topography-mediated immunomodulation in osseointegration; Ally or Enemy
S Shirazi, S Ravindran, LF Cooper - Biomaterials, 2022 - Elsevier
Osteoimmunology is at full display during endosseous implant osseointegration. Bone
formation, maintenance and resorption at the implant surface is a result of bidirectional and …
formation, maintenance and resorption at the implant surface is a result of bidirectional and …
Osteoblast differentiation and signaling: established concepts and emerging topics
M Ponzetti, N Rucci - International Journal of Molecular Sciences, 2021 - mdpi.com
Osteoblasts, the cells that build up our skeleton, are remarkably versatile and important cells
that need tight regulation in all the phases of their differentiation to guarantee proper skeletal …
that need tight regulation in all the phases of their differentiation to guarantee proper skeletal …
Exosomes derived from reparative M2-like macrophages prevent bone loss in murine periodontitis models via IL-10 mRNA
X Chen, Z Wan, L Yang, S Song, Z Fu, K Tang… - Journal of …, 2022 - Springer
Background Periodontitis is characterized by progressive inflammation and alveolar bone
loss resulting in tooth loss finally. Macrophages including pro-inflammatory M1-like …
loss resulting in tooth loss finally. Macrophages including pro-inflammatory M1-like …
Exosomal miRNA-mediated intercellular communications and immunomodulatory effects in tumor microenvironments
Extracellular communication, in other words, crosstalk between cells, has a pivotal role in
the survival of an organism. This communication occurs by different methods, one of which is …
the survival of an organism. This communication occurs by different methods, one of which is …
A review of 3D polymeric scaffolds for bone tissue engineering: principles, fabrication techniques, immunomodulatory roles, and challenges
Over the last few years, biopolymers have attracted great interest in tissue engineering and
regenerative medicine due to the great diversity of their chemical, mechanical, and physical …
regenerative medicine due to the great diversity of their chemical, mechanical, and physical …
Remotely temporal scheduled macrophage phenotypic transition enables optimized immunomodulatory bone regeneration
D Huang, K Xu, X Huang, N Lin, Y Ye, S Lin, J Zhang… - Small, 2022 - Wiley Online Library
Precise timing of macrophage polarization plays a pivotal role in immunomodulation of
tissue regeneration, yet most studies mainly focus on M2 macrophages for their anti …
tissue regeneration, yet most studies mainly focus on M2 macrophages for their anti …
Mesenchymal stem cell-macrophage crosstalk and maintenance of inflammatory microenvironment homeostasis
D Lu, Y Xu, Q Liu, Q Zhang - Frontiers in cell and developmental …, 2021 - frontiersin.org
Macrophages are involved in almost every aspect of biological systems and include
development, homeostasis and repair. Mesenchymal stem cells (MSCs) have good clinical …
development, homeostasis and repair. Mesenchymal stem cells (MSCs) have good clinical …
Immunoporosis: Role of immune system in the pathophysiology of different types of osteoporosis
W Zhang, R Gao, X Rong, S Zhu, Y Cui… - Frontiers in …, 2022 - frontiersin.org
Osteoporosis is a skeletal system disease characterized by low bone mass and altered bone
microarchitecture, with an increased risk of fractures. Classical theories hold that …
microarchitecture, with an increased risk of fractures. Classical theories hold that …
Application of bone marrow-derived macrophages combined with bone mesenchymal stem cells in dual-channel three-dimensional bioprinting scaffolds for early …
K Yu, H Huangfu, Q Qin, Y Zhang, X Gu… - … Applied Materials & …, 2022 - ACS Publications
The host immune response to biomaterials is critical for determining scaffold fate and bone
regeneration outcomes. Three-dimensional (3D) bioprinted scaffolds encapsulated with …
regeneration outcomes. Three-dimensional (3D) bioprinted scaffolds encapsulated with …
[HTML][HTML] Mesenchymal stem cells and macrophages and their interactions in tendon-bone healing
Z Chen, M Jin, H He, J Dong, J Li, J Nie, Z Wang… - Journal of Orthopaedic …, 2023 - Elsevier
Tendon-bone insertion injuries (TBI), such as anterior cruciate ligament (ACL) and rotator
cuff injuries, are common degenerative or traumatic pathologies with a negative impact on …
cuff injuries, are common degenerative or traumatic pathologies with a negative impact on …