Monoterpenes with analgesic activity—a systematic review
AG Guimarães, JSS Quintans… - Phytotherapy …, 2013 - Wiley Online Library
There is still the need for efficacious therapies for pain. In the search for new therapeutic
options, plants are a major source of novel biomolecules. Monoterpenes constitute 90% of …
options, plants are a major source of novel biomolecules. Monoterpenes constitute 90% of …
Analgesic-like activity of essential oils constituents
DP De Sousa - Molecules, 2011 - mdpi.com
Research on neuroactive drugs is a pharmaceutical sector of high interest and growth. The
discovery of efficient drugs that can relieve pain is a subject of research in the …
discovery of efficient drugs that can relieve pain is a subject of research in the …
Modulation of TRPV1 channel function by natural products in the treatment of pain
MA Abbas - Chemico-biological interactions, 2020 - Elsevier
The capsaicin (vanilloid) receptor, TRPV1, is a heat-activated cation channel modulated by
inflammatory mediators and contributes to acute and chronic pain. TRPV1 channel is one of …
inflammatory mediators and contributes to acute and chronic pain. TRPV1 channel is one of …
Peripheral and central mechanisms of orofacial inflammatory pain
BJ Sessle - International review of neurobiology, 2011 - Elsevier
Many orofacial pain conditions involve inflammation of orofacial tissues and they range from
acute pulpitis (toothache) and mucositis to chronic arthritic conditions affecting the …
acute pulpitis (toothache) and mucositis to chronic arthritic conditions affecting the …
[HTML][HTML] Improvement of p-cymene antinociceptive and anti-inflammatory effects by inclusion in β-cyclodextrin
JSS Quintans, PP Menezes, MRV Santos… - Phytomedicine, 2013 - Elsevier
Previously, we have demonstrated the analgesic-like property of p-cymene in rodents. Short
half-life is a limitation for p-cymene application and several approaches have been used to …
half-life is a limitation for p-cymene application and several approaches have been used to …
Antinociceptive Activity and Redox Profile of the Monoterpenes (+)‐Camphene, p‐Cymene, and Geranyl Acetate in Experimental Models
L Quintans-Júnior, JCF Moreira… - International …, 2013 - Wiley Online Library
Objective. To evaluate antinocicpetive and redox properties of the monoterpenes (+)‐
camphene, p‐cymene, and geranyl acetate in in vivo and in vitro experimental models …
camphene, p‐cymene, and geranyl acetate in in vivo and in vitro experimental models …
Citronellol, a monoterpene alcohol, reduces nociceptive and inflammatory activities in rodents
RG Brito, AG Guimarães, JSS Quintans… - Journal of natural …, 2012 - Springer
We describe the antinociceptive and anti-inflammatory properties of citronellol (CT) in
rodents. CT, a monoterpene alcohol, is a naturally occurring monoterpene compound …
rodents. CT, a monoterpene alcohol, is a naturally occurring monoterpene compound …
β‐Cyclodextrin‐complexed (−)‐linalool produces antinociceptive effect superior to that of (−)‐linalool in experimental pain protocols
LJ Quintans‐Júnior, RSS Barreto… - Basic & clinical …, 2013 - Wiley Online Library
Abstract Many plants produce (−)‐linalool, a plant‐derived monoterpene alcohol, including
members of the L amiaceae (mints) and L auraceae family (laurels, cinnamon, rosewood) …
members of the L amiaceae (mints) and L auraceae family (laurels, cinnamon, rosewood) …
Anti-inflammatory and Antinociceptive Activity of Epiisopiloturine, an Imidazole Alkaloid Isolated from Pilocarpus microphyllus
VG Silva, RO Silva, SRB Damasceno… - Journal of natural …, 2013 - ACS Publications
The aim of this study was to investigate the antinociceptive and anti-inflammatory activities of
epiisopiloturine (1), an imidazole alkaloid found in the leaves of Pilocarpus microphyllus …
epiisopiloturine (1), an imidazole alkaloid found in the leaves of Pilocarpus microphyllus …
α‐Terpineol reduces mechanical hypernociception and inflammatory response
MGB de Oliveira, RB Marques… - Basic & clinical …, 2012 - Wiley Online Library
Abstract α‐Terpineol (TPN), a volatile monoterpene alcohol, is relatively non‐toxic and one
of the major components of the essential oils of various plant species. In this study, we tested …
of the major components of the essential oils of various plant species. In this study, we tested …