Engineering Pyrrolysine Systems for Genetic Code Expansion and Reprogramming

DL Dunkelmann, JW Chin - Chemical Reviews, 2024 - ACS Publications
Over the past 16 years, genetic code expansion and reprogramming in living organisms has
been transformed by advances that leverage the unique properties of pyrrolysyl-tRNA …

Update of the Pyrrolysyl-tRNA Synthetase/tRNAPyl Pair and Derivatives for Genetic Code Expansion

X Gong, H Zhang, Y Shen, X Fu - Journal of Bacteriology, 2023 - Am Soc Microbiol
The cotranslational incorporation of pyrrolysine (Pyl), the 22nd proteinogenic amino acid,
into proteins in response to the UAG stop codon represents an outstanding example of …