Background Pharmacological corticosteroid therapy is the standard of care in Duchenne
Muscular Dystrophy (DMD) that aims to control symptoms and slow disease progression …

Imbalances in redox homeostasis can result in oxidative stress, which is implicated in
various pathological conditions including the fatal neuromuscular disease Duchenne …

Frameshift mutations in the DMD gene, encoding dystrophin, cause Duchenne muscular
dystrophy (DMD), leading to terminal muscle and heart failure in patients. Somatic gene …

Background Duchenne muscular dystrophy (DMD) is caused by DMD mutations leading to
dystrophin loss. Full‐length Dp427 is the primary dystrophin isoform expressed in muscle …

Background Duchenne muscular dystrophy (DMD) is the most common inherited human
myopathy. Typically, the secondary process involving severe inflammation and necrosis …

Abstract Background Adiponectin (ApN) is a hormone known to exhibit insulin‐sensitizing,
fat‐burning, and anti‐inflammatory properties in several tissues, including the skeletal …

Background Estimation of incidence in rare diseases is often challenging due to unspecific
and incomplete coding and recording systems. Patient-and health care provider-driven data …

Duchenne muscular dystrophy (DMD) is the most frequent genetic myopathy in childhood
and leads to progressive muscle atrophy, weakness, and premature death. So far, there is …

Noninvasive prenatal diagnosis (NIPD) of single-gene disorders has recently become the
focus of clinical laboratories. However, reports on the clinical application of NIPD of …

Abstract Background Aldehyde dehydrogenases (ALDHs) are key players in cell survival,
protection, and differentiation via the metabolism and detoxification of aldehydes. ALDH …