Chronic pain constitutes a significant disease burden globally and accounts for a substantial
portion of healthcare spending. The COVID-19 pandemic contributed to an increase in this …

Background Spinal mobilization (SMob) is often included in the conservative management
of spinal pain conditions as a recommended and effective treatment. While some studies …

Objective Occupational ergonomic factors (OEF) include physical exertion, demanding
posture, repetitive work, hand-arm vibration, kneeling or squatting, rising, and climbing …

Individuals with severe cartilage degeneration of the hip or knee or collapsed vertebrae that
cause spine deformities can suffer from joint and neuropathic pain in the back, disuse of the …

Although human tenocytes and dermal fibroblasts have shown promise in tendon
engineering, no tissue engineered medicine has been developed due to the prolonged ex …

Objectives: Chronic low back pain (CLBP) can seriously impair the quality of life of patients
and has a remarkable comorbidity with psychological symptoms, which, in turn, can further …

Musculoskeletal (MSK) disorders significantly burden patients and society, resulting in high
healthcare costs and productivity loss. These disorders are the leading cause of physical …

Inflammation is the hallmark of most joint disorders. However, the precise regulation of
induction, perpetuation, and resolution of joint inflammation is not entirely understood. Since …

Cyaonoside A (CyA), derived from the natural Chinese medicine, Cyathula officinalis Kuan,
which was for a long time used to treat knee injuries and relieve joint pain in traditional …

Background Osteoarthritis (OA) is the most common chronic joint disease and how
ferroptosis contributes to OA has garnered much attention recently. Bioinformatics promoted …